Persistent Maternal Mental Health Disorders and Toddler Neurodevelopment at 18 Months

One of the biggest threats to early childhood development in Africa is poor maternal mental health. The present study reports on the relationships between clinical diagnoses of persistent maternal mental health disorders (at 3- and/or 6- and 18-month post-term age) and toddler neurodevelopment at 18 months of age. Eighty-three mother-toddler dyads from low socio-economic status settings in Cape Town, South Africa, were included. At the 3-, 6- and 18-month postnatal visits, clinician-administered structured diagnostic assessments were carried out according to the Diagnostic and Statistical Manual of Mental Disorders-V (DSM-V) criteria. Toddler neurodevelopment at 18 months corrected age was assessed with the Bayley Scales of Infant and Toddler Development (BSID-III). No significant differences ( p > 0.05) were found between toddlers with exposure to persistent mood or psychotic disorders in the different BSID-III domains compared to toddlers with no exposure. Toddlers exposed to persistent comorbid anxiety and mood disorders scored significantly higher on the cognitive ( p = 0.049), motor ( p = 0.013) and language ( p = 0.041) domains and attained significantly higher fine motor ( p = 0.043) and gross motor ( p = 0.041) scaled scores compared to toddlers with no maternal mental health disorder exposure. Future investigations should focus on the role of protective factors to explain the pathways through which maternal mental health status is associated with positive toddler neurodevelopmental outcomes

Anxiety · Bayley Scales of Infant Development · Child development · Cognition · Cohort · Developmental psychology · Gross motor skill · Mental health · Mood · Mood disorders · Motor skill · Psychiatry · Psychomotor learning · Toddler · Child and Adolescent Psychosocial and Emotional Development · Infant Development and Preterm Care · Maternal Mental Health During Pregnancy and Postpartum · Medicine · Psychology · Pediatrics

• Association of Child Poverty, Brain Development, and Academic Achievement

  Open Access•Nicole L Hair, Jamie L Hanson et al.•JAMA Pediatrics•2015

  Incluir item

• Comorbidity Patterns of Anxiety and Depressive Disorders in a Large Cohort Study

  Femke Lamers, Patricia van Oppen et al.•The Journal of Clinical Psychiatry•2011

  Incluir item

• Maternal Depression and Anxiety Across the Postpartum Year and Infant Social Engagement, Fear Regulation, and Stress Reactivity

  Open Access•Rachel Feldman, Ruth Feldman et al.•Journal of the American Academy…•2009

  Incluir item

• Bayley Scales of Infant and Toddler Development, Third Edition

  Nancy Bayley•PsycTESTS Dataset•2012

  Incluir item

• Effects of perinatal mental disorders on the fetus and child

  Open Access•Alan Stein, Rebecca M Pearson et al.•The Lancet•2014

  Incluir item

• Epidemiology of maternal depression, risk factors, and child outcomes in low-income and middle-income countries

  Open Access•Bizu Gelaye, Marta B Rondon et al.•The Lancet Psychiatry•2016

  Incluir item

• The List of Threatening Experiences

  Open Access•Traolach Brugha, Paul Bebbington et al.•Psychological Medicine•1985

  Incluir item

• Effects of Poverty and Maternal Depression on Early Child Development

  Open Access•Stephen Petterson, Stephen M Petterson et al.•Child Development•2001

  Incluir item

• The Hawthorne Effect

  Open Access•Rob McCarney, James Warner et al.•BMC Medical Research Methodology•2007

  Incluir item

• Nurturing care

  Open Access•Pia R Britto, Stephen J Lye et al.•The Lancet•2017

  Incluir item

• The Lifelong Effects of Early Childhood Adversity and Toxic Stress

  Jack P Shonkoff, Andrew S Garner et al.•PEDIATRICS•2012

  Incluir item

• Detection of Postnatal Depression

  Open Access•J L Cox, J M Holden et al.•The British Journal of Psychiatry•1987

  Incluir item

• Inequalities in early childhood care and development in low/middle-income countries

  Open Access•Chunling Lu, Jorge Cuartas et al.•BMJ Global Health•2020

  Incluir item

• Chronic Maternal Depressive Symptoms Are Associated With Reduced Socio-Emotional Development in Children at 2 Years of Age

  Open Access•Clariana Vitória Ramos de Oliveira, Muneera A Rasheed et al.•Frontiers in Psychiatry•2019

  Incluir item

• Maternal common mental disorders and infant development in Ethiopia

  Open Access•Chiara Servili, Girmay Medhin et al.•BMC Public Health•2010

  Incluir item

• Maternal mental health and infant neurodevelopment at 6 months in a low‐income South African cohort

  Open Access•Marlette Burger, Christa Einspieler et al.•Infant Mental Health Journal•2022

  Incluir item

• Chronicity, severity, and timing of maternal depressive symptoms

  Patricia A Brennan, Constance Hammen et al.•Developmental Psychology•2000

  Incluir item

• Maternal depressive symptoms, mother-child interactions, and children’s executive function

  Open Access•Noa Gueron-Sela, The Family Life Project Key Investigators et al.•Developmental Psychology•2018

  Incluir item