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Deep Learning Algorithms with Lime and Similarity Distance Analysis on Covid-19 Chest X-ray Dataset

Bibliographic Data

ID15514860
AuthorsKuan-Yung Chen (Chang Bing Show Chwan Memorial Hospital), Hsi-Chieh Lee (0000-0002-9193-3513, National Quemoy University, corresponding author), Tsung-Chieh Lin (0000-0002-1307-4346, National Quemoy University), Chih-Ying Lee (0000-0001-8939-1594, National Taiwan University), Chih‐Ying Lee (0000-0002-8838-0516, National Taiwan University), Zih-Ping Ho (Chihlee Institute of Technology)
Year2023
Volume20
Issue5
Pages4330-4330
Publication date2023-02-28
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph20054330
PMID36901338
OpenAlexW4322628151
LanguageEN
References cited19

In the last few years, many types of research have been conducted on the most harmful pandemic, COVID-19. Machine learning approaches have been applied to investigate chest X-rays of COVID-19 patients in many respects. This study focuses on the deep learning algorithm from the standpoint of feature space and similarity analysis. Firstly, we utilized Local Interpretable Model-agnostic Explanations (LIME) to justify the necessity of the region of interest (ROI) process and further prepared ROI via U-Net segmentation that masked out non-lung areas of images to prevent the classifier from being distracted by irrelevant features. The experimental results were promising, with detection performance reaching an overall accuracy of 95.5%, a sensitivity of 98.4%, a precision of 94.7%, and an F1 score of 96.5% on the COVID-19 category. Secondly, we applied similarity analysis to identify outliers and further provided an objective confidence reference specific to the similarity distance to centers or boundaries of clusters while inferring. Finally, the experimental results suggested putting more effort into enhancing the low-accuracy subspace locally, which is identified by the similarity distance to the centers. The experimental results were promising, and based on those perspectives, our approach could be more flexible to deploy dedicated classifiers specific to different subspaces instead of one rigid end-to-end black box model for all feature space

Algorithm · Classifier (UML · Coronavirus disease 2019 (COVID-19 · Feature vector · Image (mathematics · Linear subspace · Machine learning · Outlier · Pattern recognition (psychology · Region of interest · Segmentation · Sensitivity (control systems · Similarity (geometry · Subspace topology · Anomaly Detection Techniques and Applications · Computer Science · COVID-19 diagnosis using AI · Mathematics · Medicine · Radiomics and Machine Learning in Medical Imaging · Artificial Intelligence

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    Open Access•Geert Litjens, Thijs Kooi et al.•Medical Image Analysis•2017

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Highly citedNo

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