Prenatal Heavy Metal Exposure and Adverse Birth Outcomes in Myanmar

A Birth-Cohort Study

Bibliographic Data

ID15515441
AuthorsKyi Mar Wai (0000-0001-8755-277X, The University of Tokyo, corresponding author), Kyi Wai (The University of Tokyo), Ohn Mar (0000-0003-4436-8993, University Of Medicine 1 Yangon), Satoko Kosaka (0000-0002-2379-2894, The University of Tokyo), Mitsutoshi Umemura (0000-0003-1734-4582, Forestry and Forest Products Research Institute), Chiho Watanabe (0000-0002-2114-3903, National Institute for Environmental Studies)
Year2017
Volume14
Issue11
Pages1339-1339
Publication date2017-11-03
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph14111339
PMID29099808
OpenAlexW2765354383
LanguageEN
Citations received5
References cited53

Arsenic, cadmium and lead are well-known environmental contaminants, and their toxicity at low concentration is the target of scientific concern. In this study, we aimed to identify the potential effects of prenatal heavy metal exposure on the birth outcomes among the Myanmar population. This study is part of a birth-cohort study conducted with 419 pregnant women in the Ayeyarwady Division, Myanmar. Face-to-face interviews were performed using a questionnaire, and maternal spot urine samples were collected at the third trimester. Birth outcomes were evaluated at delivery during the follow up. The median values of adjusted urinary arsenic, cadmium, selenium and lead concentration were 74.2, 0.9, 22.6 and 1.8 μg/g creatinine, respectively. Multivariable logistic regression revealed that prenatal cadmium exposure (adjusted odds ratio (OR) = 1.10; 95% confidence interval (CI): 1.01-1.21; p = 0.043), gestational age (adjusted OR = 0.83; 95% CI: 0.72-0.95; p = 0.009) and primigravida mothers (adjusted OR = 4.23; 95% CI: 1.31-13.65; p = 0.016) were the predictors of low birth weight. The present study identified that Myanmar mothers were highly exposed to cadmium. Prenatal maternal cadmium exposure was associated with an occurrence of low birth weight

Biology · Cohort · Cohort study · Environmental health · Gestation · Obstetrics · Pregnancy · Prenatal exposure · Child Nutrition and Water Access · Demography · Heavy Metal Exposure and Toxicity · Medicine · Trace Elements in Health · Internal Medicine

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