Clinical (BMI and MRI) and Biochemical (Adiponectin, Leptin, TNF-α, and IL-6) Effects of High-Intensity Aerobic Training with High-Protein Diet in Children with Obesity Following Covid-19 Infection

Bibliographic Data

ID15515532
AuthorsGopal Nambi (0000-0002-4203-5506, Prince Sattam Bin Abdulaziz University, corresponding author), Mshari Alghadier (0000-0003-3686-8074, Prince Sattam Bin Abdulaziz University), Tamer E Elnegamy (0000-0002-5011-8619, Prince Sattam Bin Abdulaziz University), Reem Basuodan (0000-0002-5456-2872, Princess Nourah bint Abdulrahman University), Reem M Basuodan (Princess Nourah bint Abdulrahman University), Reem M Alwhaibi (0000-0001-5950-0497, Princess Nourah bint Abdulrahman University), Arul Vellaiyan (0000-0001-5363-2472, Prince Sattam Bin Abdulaziz University), Naif A Nwihadh (Prince Sattam Bin Abdulaziz University), Osama R Aldhafian (0000-0002-9904-8447, Prince Sattam Bin Abdulaziz University), Anju Verma (0000-0003-3641-3109, The University of Sydney), Shahul Hameed Pakkir Mohamed (0000-0002-5003-7501, University of Tabuk), Mohamed Faisal Chevidikunnan (0000-0003-2316-3438, King Abdulaziz University), Fayaz Khan (0000-0003-2512-4563, King Abdulaziz University)
Year2022
Volume19
Issue12
Pages7194-7194
Publication date2022-06-11
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph19127194
OpenAlexW4282840312
LanguageEN
Citations received1
References cited35

Objective: To find the clinical and biochemical effects of high-intensity aerobic training with a high-protein diet in children with obesity following COVID-19 infection. Methods: By using the block randomization method, the eligible participants were randomized into two groups. The first group received high-intensity aerobic training with a high-protein diet (Group A; n = 38) and the second group were allowed to do regular physical activities and eat a regular diet (Group B; n = 38) for 8 weeks. Clinical (basal metabolic index (BMI) and muscle-mass-cross-sectional area (CSA)) and biochemical (Adiponectin, leptin, TNF-α, and IL-6) measures were measured at baseline, on the 8th week, and at 6-months follow-up. Results: Baseline demographic and clinical attributes show homogenous presentation among the study groups (p > 0.05). After eight weeks of intervention, and at the end of 6-months follow-up, the basal metabolic index (BMI) (6.3) (CI 95% 4.71 to 7.88), mid-arm CSA (17) (CI 95% 14.70 to 19.29), mid-thigh CSA (13.10) (CI 95% 10.60 to 15.59), mid-calf CSA (11.3) (CI 95% 9.30 to 13.29), adiponectin (−1.9) (CI 95% −2.13 to −1.66), leptin (5.64) (CI 95% 5.50 to 5.77), TNF-α (0.5) (CI 95% 0.42 to 0.57), and IL-6 (0.21) (CI 95% 0.18 to 0.23) showed more improvement (p 0.05). Conclusion: Overall, this trial found that high-intensity aerobic training with a high-protein diet decreased the BMI percentile and muscle mass (arm, thigh, and calf), and positively altered the biochemical variables in children with obesity

2019-20 coronavirus outbreak · Adiponectin · Aerobic exercise · Coronavirus disease 2019 (COVID-19 · Disease · Infectious disease (medical specialty · Insulin resistance · Intensity (physics · Leptin · Obesity · Pathology · Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 · Tumor necrosis factor alpha · Adipokines, Inflammation, and Metabolic Diseases · Adipose Tissue and Metabolism · Medicine · Regulation of Appetite and Obesity · Endocrinology · Internal Medicine

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