Childhood Leukemia in Small Geographical Areas and Proximity to Industrial Sources of Air Pollutants in Three Colombian Cities

Bibliographic Data

ID15515897
AuthorsLaura A Rodríguez-Villamizar (0000-0002-5551-2586, Industrial University of Santander, corresponding author), Feisar Enrique Moreno‐Corzo (0000-0002-5007-3422, Public Health Observatory of Santander, Fundación Oftalmológica de Santander, Floridablanca 681003, Colombia), Ana María Valbuena‐Garcia (0000-0002-3668-311X, Industrial University of Santander), Carlos Uribe (0000-0002-6640-5938, Universidad Autónoma de Bucaramanga), Claudia Janeth Uribe Pérez (Population Based Cancer Registry of the Metropolitan Area of Bucaramanga, Universidad Autónoma de Bucaramanga, Bucaramanga 681003, Colombia), Mary Ruth Brome Bohórquez (Instituto de Cancerología Las Américas), Héctor Iván García García (0000-0002-3549-1263, Instituto de Cancerología Las Américas), Luis Eduardo Bravo (0000-0002-9708-0312, Universidad del Valle), Rafael Gustavo Ortiz Martínez (0000-0002-8401-4834, Public Health Observatory of Santander, Fundación Oftalmológica de Santander, Floridablanca 681003, Colombia), Jürg Niederbacher Velásquez (Industrial University of Santander), Álvaro Osornio-Vargas (0000-0001-8287-7102, University of Alberta)
Year2020
Volume17
Issue21
Pages7925-7925
Publication date2020-10-29
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph17217925
PMID33137878
OpenAlexW3097135447
LanguageEN
Citations received2
References cited37

Acute leukemia is the most common childhood cancer and has been associated with exposure to environmental carcinogens. This study aimed to identify clusters of acute childhood leukemia (ACL) cases and analyze their relationship with proximity to industrial sources of air pollution in three capital cities in Colombia during 2000-2015. Incident ACL cases were obtained from the population cancer registries for the cities of Bucaramanga, Cali, and Medellín. The inventory of industrial sources of emissions to the air was obtained from the regional environmental authorities and industrial conglomerates were identified. The Kulldorf's circular scan test was used to detect city clusters and to identify clusters around industrial conglomerates. Multivariable spatial modeling assessed the effect of distance and direction from the industrial conglomerates controlling for socioeconomic status. We identified industrials sectors within a buffer of 1 km around industrial conglomerates related to the ACL clusters. Incidence rates showed geographical heterogeneity with low spatial autocorrelation within cities. The spatio-temporal tests identified one cluster in each city. The industries located within 1 km around the ACL clusters identified in the three cities represent different sectors. Exposure to air pollution from industrial sources might be contributing to the incidence of ACL cases in urban settings in Colombia

Air pollution · Childhood leukemia · Cluster (spacecraft · Environmental health · Geography · Incidence (geometry · Leukemia · Population · Socioeconomic status · Air Quality and Health Impacts · Global Cancer Incidence and Screening · Medicine · Occupational and environmental lung diseases

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