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An analysis of anxiety and depression in second-trimester pregnant women with cervical insufficiency

Bibliographic Data

ID15516285
AuthorsJiebing Chen (0000-0003-2482-8243, Sun Yat-sen University, corresponding author), Dayue Liu (Sun Yat-sen University), Qiqiao Du (0000-0003-4053-1044, Sun Yat-sen University), Guimei He (0000-0002-4889-0933, Sun Yat-sen University), C-F Luo (Sun Yat-sen University), Chunqi Luo (Sun Yat-sen University), Meifong Lam (Hospital Conde S. Januário), Fengchun Wu (0000-0003-2817-2341, Guangzhou Psychiatric Hospital), Jinglei Ma (Sun Yat-sen University), Yinglei Mo (Sun Yat-sen University), Junxiu Liu (0000-0003-3303-0217, Sun Yat-sen University)
Year2026
Volume17
Publication date2026-03-27
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2026.1749801
OpenAlexW7141759088
LanguageEN
References cited24

Objective Perinatal mood disorders can seriously endanger the health of pregnant women and fetuses, thus causing heavy burdens and potential hazards to families and society. This study aimed to investigate anxiety and depression in second-trimester pregnant women with cervical insufficiency and provide guidance for clinical practice. Methods A total of 136 second trimester women with cervical insufficiency who underwent laparoscopic cervical cerclage were selected as the observation group, and 117 Pregnant women with no pregnancy complications diagnosed in the second trimester of pregnancy composed the control group. In addition, both online and paper questionnaires were designed to collect basic information. Moreover, Zung’s Self-Rating Anxiety Scale and Self-Rating Depression Scale were employed to evaluate the anxiety and depression of participants in both groups. Results Pregnant women in the cervical insufficiency group had significantly higher Self-rating Anxiety Scale and Self-rating Depression Scale scores than did those in the control group (both P<0.001). Compared with those in the control group, a greater percentage of pregnant women in the cervical insufficiency group met the diagnostic criteria for anxiety and depression. The multivariate linear regression model revealed that cervical insufficiency and a history of abnormal pregnancy were related to higher Self-rating Anxiety Scale scores, whereas a history of abnormal pregnancy was also associated with higher Self-rating Depression Scale scores (both P<0.05). Conclusion Pregnant women with cervical insufficiency are more likely to suffer from anxiety and depression in the second trimester than normal pregnant women are. Healthcare professionals should pay more attention to these patients in clinical practice

Anxiety · Cervical insufficiency · Depression (economics · Edinburgh Postnatal Depression Scale · Hospital Anxiety and Depression Scale · Mood · Mood disorders · Pregnancy · Maternal Mental Health During Pregnancy and Postpartum · Preterm Birth and Chorioamnionitis · Reproductive tract infections research

  • A Rating Instrument For Anxiety Disorders

    Open Access•William W K Zung•Psychosomatics•1971

  • Influencing factors of depressive symptoms during pregnancy in Beijing, China

    Open Access•Xiayue He, Xiaoqian Wang et al.•Frontiers in Psychiatry•2025

  • An Analysis on the Factors for Cervical Insufficiency Causing Adverse Emotions Among Pregnant Women at Different Gestation Phases

    Open Access•Qichang Wu, Jiebing Chen et al.•Frontiers in Psychiatry•2022

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