Driving-related cognitive skills during antidepressant transcranial direct current stimulation
Results in a subsample from the DepressionDC trial
Bibliographic Data
| ID | 15516609 |
|---|---|
| Authors | Gerrit Burkhardt (0000-0003-3965-5664, LMU Klinikum, corresponding author), Stephan Goerigk (0000-0002-3021-0346, LMU Klinikum), Esther Dechantsreiter (0009-0002-0674-4572, LMU Klinikum), Lucia Bulubas (0000-0002-5797-8742, Ludwig-Maximilians-Universität München), Aldo Soldini (0009-0000-5460-0747, Ludwig-Maximilians-Universität München), Peter Zwanzger (0000-0002-5385-8188, Inn-Salzach-Klinikum), Julia Diemer (0000-0002-5787-971X, Inn-Salzach-Klinikum), Frank Padberg (0000-0001-7638-8310, LMU Klinikum), Alexander Brunnauer (Inn-Salzach-Klinikum), Ulrike Kumpf (LMU Klinikum) |
| Year | 2023 |
| Volume | 14 |
| Pages | 1255415-1255415 |
| Publication date | 2023-12-07 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Psychiatry (JOURNAL) |
| Journal identifiers | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Publisher | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2023.1255415 |
| PMID | 38130292 |
| OpenAlex | W4389436943 |
| Language | EN |
| References cited | 21 |
Therapeutic transcranial direct current stimulation (tDCS) is a well-tolerated neuromodulatory intervention. However, there are currently no data on its impact on driving skills. Therefore, we conducted a validated assessment of driving-related cognitive skills in participants of the DepressionDC trial, a multicenter, randomized-controlled trial investigating the antidepressant effects of 6-week prefrontal tDCS in patients with major depressive disorder (MDD). Twenty-one patients (12 women, active tDCS, n = 11, sham, n = 10) underwent an assessment of driving-related cognitive skills before and after the intervention. Using a Bayesian analysis approach, we found no group differences between active tDCS and sham tDCS in the pre-post treatment changes for visual perception (estimated median difference: 3.41 [-3.17, 10.55 89%-CI], BF 01 : 2.1), stress tolerance (estimated median difference: 0.77 [-2.40, 4.15 89%-CI], BF 01 : 1.6), and reaction time (estimated median difference: 2.06 [-12.33, 16.83 89%-CI], BF 01 : 6.5). Our results indicate that repeated sessions of a conventional bifrontal tDCS protocol do not negatively impact driving-related cognitive skills in patients with MDD
Antidepressant · Brain stimulation · Cognition · Hippocampus · Stimulation · Transcranial Direct Current Stimulation · Transcranial magnetic stimulation · Medicine · Neural and Behavioral Psychology Studies · Neuroscience · Psychology · Spatial Neglect and Hemispheric Dysfunction · Transcranial Magnetic Stimulation Studies
| Highly cited | No |
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