Potential therapeutic effects of an ayahuasca-inspired N,N-DMT and harmine formulation

A controlled trial in healthy subjects

Bibliographic Data

ID15516669
AuthorsHelena Aicher (0000-0001-5915-7086, University of Zurich, corresponding author), Helena D Aicher, Michael J Mueller (0000-0001-9165-0903, ETH Zurich), Dario Dornbierer (0000-0001-9946-2069, University of Zurich), Dario A Dornbierer, Dila Suay (0000-0002-5268-9992, IMT School for Advanced Studies Lucca), Claudius Elsner (University of Zurich), Ilhui A Wicki (0000-0002-5511-7981, University of Zurich), Ilhui Wicki, Daniel Meling (0000-0001-9118-5431, University of Freiburg), Luzia Caflisch (University of Zurich), Alexandra Hempe (University of Zurich), C R Steinhart (University of Zurich), Camilla Steinhart, Jovin Mueller (University of Zurich), Robin von Rotz (0000-0003-4087-3650, University of Zurich), Birgit Kleim (0000-0001-9114-2917, University of Zurich), Milan Scheidegger (0000-0003-1313-2208, University of Zurich)
Year2024
Volume14
Pages1302559-1302559
Publication date2024-01-08
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2023.1302559
PMID38264636
OpenAlexW4390825728
LanguageEN
Citations received3
References cited86

Our results suggest that the experience induced by the standardized DMT + harmine formulation induces a phenomenologically rich psychedelic experience, demonstrates good psychological safety and tolerability, is well tolerated, and induces beneficial psychological processes that could possibly support psychotherapy. Further studies are required to investigate the psychotherapeutic potential in patients

Ayahuasca · Biology · Harmine · Psychotherapist · Traditional medicine · Biochemical Analysis and Sensing Techniques · Chemical synthesis and alkaloids · Clinical Psychology · Medicine · Psychedelics and Drug Studies · Psychology · Pharmacology

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