Altered Gray-Matter Volumes Associated With Betel Quid Dependence
Bibliographic Data
| ID | 15516693 |
|---|---|
| Authors | Fulai Yuan (Xiangya Hospital Central South University), Lingyu Kong (0000-0001-5952-005X, Central South University), Xueling Zhu (0000-0002-3731-4682, Xiangya Hospital Central South University), Canhua Jiang (0000-0002-8133-1981, Central South University), Changyun Fang (0000-0002-2879-6587, Xiangya Hospital Central South University), Weihua Liao (0000-0002-1926-3527, Xiangya Hospital Central South University, corresponding author) |
| Year | 2017 |
| Volume | 8 |
| Pages | 139-139 |
| Publication date | 2017-08-03 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Psychiatry (JOURNAL) |
| Journal identifiers | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Publisher | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2017.00139 |
| PMID | 28824470 |
| OpenAlex | W2740043863 |
| Language | EN |
| Citations received | 5 |
| References cited | 69 |
Betel quid (BQ) is one of the most commonly consumed psychoactive substances. It has been suggested to be associated with various health issues, especially oral cancer. Evidence also points to possible decreased cognitive functions after long-term BQ chewing, such as attention and inhibition control. The present study aims to investigate the brain structure basis of BQ chewing in Hunan province of China. Twenty-five BQ chewers and 25 controls were recruited to participate in this study. Voxel-based morphormetry analysis revealed that there were three key regions showing structural differences between BQ chewers and controls, including bilateral dorsolateral prefrontal cortex (DLPFC)/insula, ventral medial prefrontal cortex, and left orbitofrontal cortex. Moreover, the GMV in the DLPFC could potentially predict BQ dependence scores, level of daily BQ chewing, and history of BQ chewing. These results suggested that participants who showed BQ chewing dependence may have deficit in inhibition control and affective decision-making, and the level of deficit was dependent on the level of daily BQ chewing, and history of BQ chewing. Understanding the neurobiology features of BQ chewing would help us develop novel ways to diagnose and prevent BQ dependence
Insula · Magnetic resonance imaging · Mastication · Radiology · Voxel-based morphometry · White matter · Dentistry · Medicine · Neuroscience · Oral Health Pathology and Treatment · Plant-based Medicinal Research · Psychology · Salivary Gland Disorders and Functions
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| Citations per year | 0.56 |
|---|---|
| Citation span | 2017 - 2022 (6) |
| Highly cited | No |