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Ketamine assisted psychotherapy in postpartum mood and anxiety disorders

A limited case series

Bibliographic Data

ID15517004
AuthorsAlka Christnacht (Seattle University), Therry Rose Eparwa (Integrative Medicine Institute), Emily Whinkin (Integrative Medicine Institute, corresponding author), Sunil Aggarwal (University of Washington)
Year2026
Volume16
Pages1661604-1661604
Publication date2026-01-22
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2025.1661604
PMID41659180
OpenAlexW7125419807
LanguageEN
References cited46

The postpartum period is notorious for rapid and profound changes for birthing individuals and their families. Significant shifts to hormonal and physical health, routines and family roles, and the salience of personal and community risk factors all contribute to potential psychiatric and psychological distress for parents, sometimes diagnosed as a postpartum mood or anxiety disorder (PMAD). Existing pharmacologic treatment modalities for PMADs do not comprehensively address the profound shifts of the postpartum period, often inadequate at reaching peak therapeutic efficacy in a shorter time frame, in patient accessibility, or offering sustained benefit. Ketamine assisted psychotherapy (KAP), is increasingly recognized as a therapeutic option for a range of psychiatric disorders and has been explored as a modality to prevent PMADs when used during Cesarean births. This retrospective case series examines three cases where ketamine assisted psychotherapy (KAP) was introduced during the first two years postpartum as part of a comprehensive treatment plan for PMADs. This study describes the utility of ketamine assisted psychotherapy to the postpartum individual, and offers perspective on the impact of psychedelic insights through treatment of PMAD symptoms

Anxiety · Distress · Ketamine · Modalities · Mood · Postpartum depression · Postpartum period · Maternal Mental Health During Pregnancy and Postpartum · Psychedelics and Drug Studies · Treatment of Major Depression

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    Open Access•Philip E Wolfson, Rob Cole et al.•Journal of Psychoactive Drugs•2022

  • Ketamine Assisted Psychotherapy (KAP)

    Open Access•Jennifer Dore, Brent Turnipseed et al.•Journal of Psychoactive Drugs•2019

  • Metabolism and metabolomics of ketamine

    Open Access•John Fenwick, Ricardo Jorge Dinis-Oliveira et al.•Forensic Sciences Research•2017

Highly citedNo

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