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Acute hepatitis B virus infection in pregnancy

A case report of three patients with comorbid anxiety and their clinical outcomes

Bibliographic Data

ID15517294
AuthorsShanshan Wu (0000-0002-2339-7763, Zhejiang Chinese Medical University), Shenlu Wu, Klücken Hu (Third People's Hospital of Hangzhou), Kejie Hu, Yufang Wang (0000-0001-7725-4533, Third People's Hospital of Hangzhou, corresponding author)
Year2025
Volume16
Pages1695165-1695165
Publication date2025-10-22
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2025.1695165
PMID41200228
OpenAlexW4415418920
LanguageEN
Citations received1
References cited30

This case series reports three pregnant women with acute hepatitis B virus (AHB) infection, exploring their clinical outcomes and comorbid anxiety. All three patients presented with abnormal liver function and positive HBV markers. They received supportive therapy (liver-protective, enzyme-lowering agents, etc.), achieving HBsAg clearance and virological cure, with normal liver function during follow-up (one patient lost to follow-up). Despite favorable biomedical outcomes, all experienced significant anxiety over maternal-fetal health and disease progression. This study emphasizes that AHB in pregnancy, though usually self-limited, requires integrating psychosocial support into multidisciplinary management to address perinatal mental health, supporting WHO's 2030 viral hepatitis elimination goal

Anxiety · Depression (economics · Disease · HBsAg · Hepatitis B · Hepatitis B virus · Mental health · Psychosocial · Psychosocial support · Hepatitis B Virus Studies · Hepatitis Viruses Studies and Epidemiology · Liver Disease Diagnosis and Treatment

  • Using latent class analysis to characterize a high-misconception profile for targeted health education among HBsAg-positive pregnant women in China

    Open Access•Gaiyan Du, Ping Zhang et al.•Frontiers in Public Health•2026

  • Elevated depression and anxiety symptoms among pregnant individuals during the Covid-19 pandemic

    Open Access•Charles Lebel, Catherine Lebel et al.•Journal of Affective Disorders•2020

Citations per year1
Citation span2026 - 2026 (1)
Highly citedNo

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