Causal associations between severe mental illness and sepsis
A Mendelian randomization study
Bibliographic Data
| ID | 15517801 |
|---|---|
| Authors | Ruhao Yang (Wuhan University, corresponding author), Hongyu Xiang (0000-0001-5953-1293, Wuhan University), Ting Zheng (0000-0003-4757-9075, Wuhan University, corresponding author) |
| Year | 2024 |
| Volume | 15 |
| Pages | 1341559-1341559 |
| Publication date | 2024-03-12 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Psychiatry (JOURNAL) |
| Journal identifiers | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Publisher | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2024.1341559 |
| PMID | 38532990 |
| OpenAlex | W4392715752 |
| Language | EN |
| References cited | 44 |
Our research revealed a suggestive association between genetically predicted major depression and an elevated risk of sepsis in individuals of European ancestry. This finding can serve as a reminder for clinicians to consider the possibility of subsequent infection and sepsis in depressive patients, which may help reduce the incidence of sepsis in individuals with depression
Biology · Gene · Genetic association · Genetic variants · Genome-wide association study · Genotype · Major depressive disorder · Mendelian randomization · Observational study · Pleiotropy · Psychiatry · Schizophrenia (object-oriented programming · Sepsis · Single-nucleotide polymorphism · Gut microbiota and health · Medicine · Sepsis Diagnosis and Treatment · Tryptophan and brain disorders · Genetics · Internal Medicine
From inflammation to sickness and depression
Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
Global, regional, and national sepsis incidence and mortality, 1990–2017
Years of potential life lost and life expectancy in schizophrenia
Association Between Depression and Elevated C-Reactive Protein
Anxiety and Depression Symptoms in a General Population and Future Risk of Bloodstream Infection
Psychosocial Stress as a Risk Factor for Sepsis
Dying Too Soon
| Highly cited | No |
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