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Intravenous ketamine for depression

A clinical discussion reconsidering best practices in acute hypertension management

Bibliographic Data

ID15518751
AuthorsRyan Yip (University of Alberta), Jennifer Swainson (0000-0002-6071-1395, Misericordia Community Hospital), Atul Khullar (Grey Nuns Community Hospital), Roger S McIntyre (0000-0003-4733-2523, Brain and Cognition Discovery Foundation), Kevin Skoblenick (0000-0003-4404-0234, Women and Children’s Health Research Institute, corresponding author)
Year2022
Volume13
Pages1017504-1017504
Publication date2022-09-29
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2022.1017504
PMID36245888
OpenAlexW4298005428
LanguageEN
Citations received2
References cited38

Ketamine is a versatile medication with an emerging role for the treatment of numerous psychiatric conditions, including treatment resistant depression. Current psychiatry guidelines for its intravenous administration to treat depression recommend regular blood pressure monitoring and an aggressive approach to potential transient hypertensive episodes induced by ketamine infusions. While this approach is aimed at ensuring patient safety, it should be updated to align with best practice guidelines in the management of hypertension. This review defines and summarizes the currently recommended approach to the hypertensive emergency, the asymptomatic hypertensive urgency, and discusses their relevance to intravenous ketamine therapy. With an updated protocol informed by these best practice guidelines, ketamine treatment for depression may be more accessible to facilitate psychiatric treatment

Alternative medicine · Best practice · Blood pressure · Clinical Practice · Depression (economics · Intensive care medicine · Ketamine · Management of depression · Physical therapy · Protocol (science · Psychiatry · Electroconvulsive Therapy Studies · Medicine · Treatment of Major Depression · Tryptophan and brain disorders · Internal Medicine

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Unique citing works2
Citations per year0,67
Citation span2023 - 2024 (2)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 2
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