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D-AI mouse behavior analysis system has the capability to detect abnormalities in R6/1 model mice with Huntington’s disease during the pre-symptomatic phase

Bibliographic Data

ID15518753
AuthorsShida Zhou (Shenzhen Institutes of Advanced Technology, a, corresponding author), Xiaoyu Wang (0000-0002-6800-1275, Shenzhen University Health Science Center), Yu Tian Wang (0000-0001-8592-0698, Fudan University)
Year2026
Volume17
Pages1749543-1749543
Publication date2026-03-10
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2026.1749543
PMID41883719
OpenAlexW7134806058
LanguageEN
References cited38

These results establish precision behavioral analytics as a sensitive platform for detecting premanifest HD pathology, providing a framework for evaluating presymptomatic therapeutics and scientific base for developing early diagnostic and treatment strategies for HD

Anxiety · Cognition · Disease · Gait analysis · Genetically modified mouse · Huntington's disease · Mirroring · Sniffing · Amyotrophic Lateral Sclerosis Research · Genetic Neurodegenerative Diseases · Neurological disorders and treatments

Highly citedNo

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