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Mitragynine Attenuates Morphine Withdrawal Effects in Rats—A Comparison With Methadone and Buprenorphine

Bibliographic Data

ID15519169
AuthorsRahimah Hassan (Universiti Sains Malaysia), Pike-See Cheah (0000-0003-2181-2502, Universiti Putra Malaysia), Cheah Pike See, Sreenivasan Sasidharan (0000-0002-7705-1418, Universiti Sains Malaysia), Sasidharan Sreenivasan, Sharif Mahsufi Mansor (Universiti Sains Malaysia), Christian P Müller (0000-0002-5325-9900, Friedrich-Alexander-Universität Erlangen-Nürnberg, corresponding author), Zurina Hassan (0000-0003-3205-4612, Universiti Sains Malaysia, corresponding author)
Year2020
Volume11
Pages411-411
Publication date2020-05-07
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2020.00411
PMID32457670
OpenAlexW3023048099
LanguageEN
Citations received3
References cited91

These data suggest that mitragynine may be a potential drug candidate for opiate withdrawal treatment

Abstinence · Abstinence Syndrome · Addiction · Anesthesia · Buprenorphine · Methadone · Morphine · Opiate · Opioid · Physical dependence · Psychiatry · Alkaloids: synthesis and pharmacology · Chemical synthesis and alkaloids · Medicine · Traditional and Medicinal Uses of Annonaceae · Internal Medicine · Pharmacology

  • Association between kratom ( Mitragyna speciosa Korth.) use and methamphetamine craving in males who used methamphetamine with and without heroin use history

    Open Access•Yuting Yang, Christian P Müller et al.•Journal of Ethnicity in Substance…•2026

  • Aggression in a Cohort of Male Methamphetamine (Meth) Users With and Without Kratom ( Mitragyna speciosa Korth.) Use History in Malaysia

    Yuting Yang, Christian P Müller et al.•Journal of Psychoactive Drugs•2026

  • Exploring adolescents’ practice and perspective on the use and misuse of kratom in northwest Malaysia

    Karniza Khalid, Salwana Ku Md Saad et al.•Journal of Ethnicity in Substance…•2021

  • Mitragynine inhibits the COX-2 mRNA expression and prostaglandin E2 production induced by lipopolysaccharide in RAW264.7 macrophage cells

    Open Access•Zulkhurnain Utar, Mohamed Isa Abdul Majid et al.•Journal of Ethnopharmacology•2011

  • The effect of mitragynine on cAMP formation and mRNA expression of mu-opioid receptors mediated by chronic morphine treatment in SK–N–SH neuroblastoma cell

    Open Access•Mohd Fadzly Amar Jamil, Mohd Ferdaues Mohd Subki et al.•Journal of Ethnopharmacology•2013

  • Evaluating the hematological and clinical-chemistry parameters of kratom (Mitragyna speciosa) users in Malaysia

    Open Access•Darshan Singh, Christian P Müller et al.•Journal of Ethnopharmacology•2018

  • Effects of mitragynine from Mitragyna speciosa Korth leaves on working memory

    Open Access•Evhy Apryani, Mohamad Taufik Hidayat et al.•Journal of Ethnopharmacology•2010

  • Subchronic exposure to mitragynine, the principal alkaloid of Mitragyna speciosa, in rats

    Open Access•Azadeh Sabetghadam, Surash Ramanathan et al.•Journal of Ethnopharmacology•2013

  • Social Functioning of Kratom (Mitragyna speciosa) Users in Malaysia

    Darshan Singh, Christian P Müller et al.•Journal of Psychoactive Drugs•2015

  • Severity of Kratom ( Mitragyna speciosa Korth.) Psychological Withdrawal Symptoms

    Darshan Singh, Suresh Narayanan et al.•Journal of Psychoactive Drugs•2018

  • Long-Term Cognitive Effects of Kratom ( Mitragyna speciosa Korth.) Use

    Darshan Singh, Suresh Narayanan et al.•Journal of Psychoactive Drugs•2018

Unique citing works3
Citations per year0,6
Citation span2021 - 2026 (6)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 2
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