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Adverse childhood experience and depression

The role of gut microbiota

Bibliographic Data

ID15519257
AuthorsYu Bai (0000-0003-1707-3081, Wuhan University), Chang Shu (0000-0002-7880-9681, Renmin Hospital of Wuhan University), Ying Hou (0000-0002-9303-284X, China-Japan Friendship Hospital), Gaohua Wang (0000-0002-8947-9921, Renmin Hospital of Wuhan University, corresponding author)
Year2024
Volume15
Pages1309022-1309022
Publication date2024-04-02
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2024.1309022
PMID38628262
OpenAlexW4393425766
LanguageEN
Citations received5
References cited6

Depression is the most common psychiatric disorder that burdens modern society heavily. Numerous studies have shown that adverse childhood experiences can increase susceptibility to depression, and depression with adverse childhood experiences has specific clinical-biological features. However, the specific neurobiological mechanisms are not yet precise. Recent studies suggest that the gut microbiota can influence brain function and behavior associated with depression through the "microbe-gut-brain axis" and that the composition and function of the gut microbiota are influenced by early stress. These studies offer a possibility that gut microbiota mediates the relationship between adverse childhood experiences and depression. However, few studies directly link adverse childhood experiences, gut microbiota, and depression. This article reviews recent studies on the relationship among adverse childhood experiences, gut microbiota, and depression, intending to provide insights for new research

Adverse Childhood Experiences · Adverse effect · Depression (economics · Gut flora · Gut–brain axis · Mental health · Psychiatry · Gut microbiota and health · Medicine · Psychology · Schizophrenia research and treatment · Tryptophan and brain disorders · Immunology · Internal Medicine

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Unique citing works5
Citations per year5
Citation span2025 - 2026 (2)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 5

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