Clinical efficacy of modified suanzaoren decoction compared to esazolam tablets in the treatment of chronic insomnia disorder

Bibliographic Data

ID15519333
AuthorsPing Yao (0000-0001-8837-9630, Inner Mongolia Autonomous Region Hospital of Traditional Chinese Medicine), Xiao Guo (0000-0002-0533-3547, Inner Mongolia People's Hospital), Xingyan Guo, Zhiguo Guo (0000-0002-6053-1263, Inner Mongolia Autonomous Region Hospital of Traditional Chinese Medicine), Wuhong Lin (Inner Mongolia People's Hospital), Min Liu (0000-0002-6622-5486, Inner Mongolia Autonomous Region Hospital of Traditional Chinese Medicine), Min Chen (0000-0001-8922-8789, Inner Mongolia People's Hospital), Jie Li (0000-0002-5131-4769, Inner Mongolia People's Hospital), Long-Biao Cui (Air Force Medical University, corresponding author), Dongsheng Lv (0000-0002-1559-3588, Fourth Hospital of Inner Mongolia, corresponding author)
Year2025
Volume16
Pages1533652-1533652
Publication date2025-07-24
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2025.1533652
PMID40778328
OpenAlexW4412645322
LanguageEN
References cited29

After the treatment of CID with the modified SZRD and esazolam, they have the comparable clinical efficacy. However, estazolam showed a more consistent treatment effect in subjective sleep quality assessment among the study population, whereas modified SZRD showed a more consistent treatment effect in objective slow-wave sleep maintenance, specifically in N3 stage duration. The registration number was NCT06452953

Anxiety · Decoction · Depression (economics · Insomnia · Pittsburgh Sleep Quality Index · Polysomnography · Psychiatry · Sleep quality · Circadian rhythm and melatonin · Medicine · Psychology · Sleep and related disorders · Sleep and Wakefulness Research · Internal Medicine