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Autism Rating Scale

A New Tool for Characterizing the Schizophrenia Phenotype

Bibliographic Data

ID15519373
AuthorsDavide Palumbo (0000-0001-6373-2741, University of Campania "Luigi Vanvitelli"), Giovanni Stanghellini (0000-0001-5164-7013, Diego Portales University), Armida Mucci (0000-0002-6195-9456, University of Campania "Luigi Vanvitelli", corresponding author), Massimo Ballerini, Giulia Maria Giordano (0000-0002-5247-1117, University of Campania "Luigi Vanvitelli"), Paul H Lysaker (0000-0002-6617-9387, Richard L. Roudebush VA Medical Center), Silvana Galderisi (0000-0002-1592-7656, University of Campania "Luigi Vanvitelli")
Year2021
Volume12
Pages622359-622359
Publication date2021-01-26
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2021.622359
PMID33574776
OpenAlexW3121344422
LanguageEN
Citations received1
References cited41

Social dysfunctions (SD) are frequently observed in subjects with schizophrenia. Some of these dysfunctions are also observed in other neuropsychiatric disorders such as autism spectrum disorders (ASD), major depression, bipolar disorder, or Alzheimer disease. Recently, a characterization of a specific type of SD in schizophrenia has been proposed, with the concept of dis-sociality, which form the core aspect of "Schizophrenic Autism" (SA). The present study aimed to explore the presence in people with schizophrenia of SA, independent of other autistic traits, which can be often found in schizophrenia and other neurodevelopmental disorders. We used a structured interview-the Autism Rating Scale (ARS), an instrument devised to detect and measure SA. Fifty-one outpatients affected by schizophrenia (26 remitted, SCZ-r) and 28 affected by bipolar disorder type 1, with psychotic features, in the euthymic phase (BD-e) were recruited. Before assessing the specificity for schizophrenia of SA, we tested the internal consistency, the convergent and divergent validity of the ARS in the schizophrenia sample. Specificity was assessed by examining potential differences in ARS scores between SCZ-r and BD-e subjects. ARS showed good internal consistency, as well as convergent and divergent validity. ARS items were more frequently of moderate severity in SCZ-r than in BD-e subjects. This scale can contribute to establish more precise phenomenal boundaries between schizophrenia and bipolar disorder, and opens up the possibility of identifying a different type of SD in schizophrenia, independent of autistic traits and negative symptoms, which might benefit from different treatments

Autism · Autism spectrum disorder · Bipolar disorder · Cognition · Convergent validity · Developmental psychology · Internal consistency · Psychiatry · Psychometrics · Psychosis · Rating scale · Schizophrenia (object-oriented programming · Autism Spectrum Disorder Research · Clinical Psychology · Obsessive-Compulsive Spectrum Disorders · Psychology · Schizophrenia research and treatment

  • The Relationship Between the Recognition of Basic Emotions and Negative Symptoms in Individuals With Schizophrenia Spectrum Disorders – An Exploratory Study

    Open Access•Marco Zierhut, Kerem Böge et al.•Frontiers in Psychiatry•2022

  • Prevalence of co-occurring mental health diagnoses in the autism population

    Open Access•Meng-Chuan Lai, Caroline Kassee et al.•The Lancet Psychiatry•2019

  • Remission in Schizophrenia

    Nancy C Andreasen, Will Tom Carpenter et al.•American Journal of Psychiatry•2005

  • The Positive and Negative Syndrome Scale (PANSS) for Schizophrenia

    Stanley R Kay, Abraham Fiszbein et al.•Schizophrenia Bulletin•1987

Unique citing works1
Citations per year0,25
Citation span2022 - 2022 (1)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 1

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