Negative Effects of a Multimodal Inpatient CBASP Program

Rate of Occurrence and Their Impact on Treatment Outcome in Chronic and Treatment-Resistant Depression

Bibliographic Data

ID15519555
AuthorsPhilipp Herzog (0000-0002-8267-2083, Philipps University of Marburg), Sophia Häusler (Philipps University of Marburg), Claus Normann (0000-0001-5693-8936, University Medical Center Freiburg), Eva-Lotta Brakemeier (0000-0001-9589-3697, Justus-Liebig-Universität Gießen, corresponding author)
Year2021
Volume12
Pages575837-575837
Publication date2021-08-09
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2021.575837
PMID34434122
OpenAlexW3189777813
LanguageEN
Citations received3
References cited48

Background: A growing number of studies indicate that the Cognitive Behavioral Analysis System of Psychotherapy (CBASP) is effective in treating chronic depression. However, there is no systematic research into possible negative effects. Therefore, the objectives of the study were to investigate the rate of occurrence of negative effects of an inpatient CBASP program and their impact on treatment response. Methods: Patients with chronic depression and treatment resistance who completed the 12-week multimodal inpatient CBASP treatment program in an open trial ( N = 52) retrospectively completed the Inventory for the Assessment of Negative Effects of Psychotherapy (INEP) during follow-up data collection. Severity of depressive symptoms was assessed self- and observer-rated at admission, discharge, and 6 months follow-up. Rates of occurrence of negative effects were calculated and binary logistic regression analyses were conducted to determine the relationship to treatment outcome. Results: The results indicate that 92.3% of patients reported having experienced at least one negative effect and 45.2% indicated dependence on their therapist. Stigmatization and financial concerns as well as intrapersonal changes were reported by about one-third. Only dependence on the therapist negatively impacted treatment outcome in both outcome measures. Conclusions: While almost all patients reported at least one negative effect of a multimodal inpatient CBASP treatment program, most of the reported negative effects appear to be benign. However, dependence on the therapist seems to have a negative impact on treatment outcome. If these results can be replicated in future large-scale, randomized controlled prospective studies, CBASP therapists should be aware of possible dependence and consciously address it during treatment

Chronic depression · Cognition · Depression (economics · Depressive symptoms · Interpersonal communication · Intrapersonal communication · Logistic regression · Outcome (game theory · Psychiatry · Randomized controlled trial · Treatment and control groups · Clinical Psychology · Medicine · Mental Health Research Topics · Personality Disorders and Psychopathology · Psychology · Psychotherapy Techniques and Applications · Internal Medicine

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