Evidence for increased DNA damage repair in the postmortem brain of the high stress-response group of schizophrenia
Bibliographic Data
| ID | 15519580 |
|---|---|
| Authors | Risa Shishido (Fukushima Medical University), Yasuto Kunii (0000-0003-1569-7819, Fukushima Medical University, corresponding author), Mizuki Hino (0000-0003-3700-0322, Fukushima Medical University), Ryuta Izumi (0000-0002-8453-3474, Fukushima Medical University), Atsuko Nagaoka (0000-0002-1159-4436, Fukushima Medical University), Hideki Hayashi (0000-0002-4693-9801, Niigata University), Akiyoshi Kakita (0000-0003-4244-0277, Niigata University), Hiroaki Tomita (0000-0003-2628-880X, Tohoku University), Hirooki Yabe (0000-0003-2668-129X, Fukushima Medical University) |
| Year | 2023 |
| Volume | 14 |
| Pages | 1183696-1183696 |
| Publication date | 2023-08-22 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Psychiatry (JOURNAL) |
| Journal identifiers | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Publisher | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2023.1183696 |
| PMID | 37674553 |
| OpenAlex | W4386070413 |
| Language | EN |
| References cited | 59 |
Our results suggest that there are subgroups of SZ with different degrees of stress impact. Furthermore, the pathophysiology of these subgroups may be associated with DNA damage repair. These results provide new insights into the interactions and heterogeneity between genetic and environmental factors
Biology · DNA damage · Glucocorticoid receptor · Population · Prefrontal cortex · Receptor · Medicine · Neuroinflammation and Neurodegeneration Mechanisms · Neuroscience · Stress Responses and Cortisol · Tryptophan and brain disorders · Endocrinology · Genetics · Internal Medicine
| Citation velocity | historical |
|---|---|
| Highly cited | No |