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Effects of Xiaoyaosan on Depressive-Like Behaviors in Rats With Chronic Unpredictable Mild Stress Through HPA Axis Induced Astrocytic Activities

Bibliographic Data

ID15519615
AuthorsMing Song (0000-0001-8459-6953, Beijing University of Chinese Medicine), Jianjun Zhang (0000-0001-9357-6778, Beijing University of Chinese Medicine), Xiaojuan Li (0000-0002-7510-6593, Beijing University of Chinese Medicine), Yueyun Liu (Beijing University of Chinese Medicine), Tingye Wang (Beijing University of Chinese Medicine), Zhiyi Yan (0000-0001-9828-7705, Beijing University of Chinese Medicine), Jiaxu Chen (0000-0002-5570-6233, Beijing University of Chinese Medicine, corresponding author)
Year2020
Volume11
Pages545823-545823
Publication date2020-10-20
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2020.545823
PMID33192662
OpenAlexW3093480532
LanguageEN
Citations received3
References cited48

Changes in the hippocampus GFAP and Glu-NMDA receptor may be an essential mechanism of depression. Besides, XYS may be critical to the treatment of depression by intervention the HPA axis, GFAP and Glu-NMDA receptor

Antidepressant · Astrocyte · Behavioural despair test · Central nervous system · Chronic stress · Corticosterone · Fluoxetine · Glial fibrillary acidic protein · Glucocorticoid receptor · Hippocampal formation · Hippocampus · Hormone · Immunohistochemistry · NMDA receptor · Open field · Receptor · Serotonin · Chemistry · Medicine · Neuroendocrine regulation and behavior · Stress Responses and Cortisol · Tryptophan and brain disorders · Endocrinology · Internal Medicine

  • Modified Xiaoyao San reverses lipopolysaccharide-induced depression-like behavior through suppressing microglia M1 polarization via enhancing autophagy involved in PI3K/Akt/mTOR pathway in mice

    Open Access•Pan Su, Mengdi Wu et al.•Journal of Ethnopharmacology•2023

  • The molecular mechanism of Xiaoyaosan in treating major depressive disorder

    Open Access•Rongyanqi Wang, Tan Zou et al.•Journal of Ethnopharmacology•2025

  • Xiaoyaosan ethyl acetate fraction alleviates depression-like behaviors in Cums mice by promoting hippocampal neurogenesis via modulating the IGF-1Rβ/PI3K/Akt signaling pathway

    Open Access•Jiuseng Zeng, Yafei Ji et al.•Journal of Ethnopharmacology•2022

  • Prevalence and psychometric screening for the detection of major depressive disorder and post-traumatic stress disorder in adults injured in a motor vehicle crash who are engaged in compensation

    Open Access•Rebecca Guest, Yvonne Tran et al.•BMC Psychology•2018

  • Effects of Xiaoyaosan on the Hippocampal Gene Expression Profile in Rats Subjected to Chronic Immobilization Stress

    Open Access•Xiaohong Li, Xiao-Hong Li et al.•Frontiers in Psychiatry•2019

Unique citing works3
Citations per year0,75
Citation span2022 - 2025 (4)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 3

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