Five differentially expressed proteins identified to serve as potential blood biomarkers for schizophrenia screening based on proteomics
Bibliographic Data
| ID | 15519804 |
|---|---|
| Authors | Ronghua Li (0000-0002-3105-5325, Soochow University), Xiaoqian Fu (0000-0003-0753-2168, Soochow University), Chuanwei Li (0000-0001-5982-3237, Soochow University), Lian Yuan (Soochow University), Yaozhi Liu (North Sichuan Medical University), Lin Yang (0000-0002-1698-6666, Soochow University), Xiaojia Fang (Soochow University), Xiaobin Zhang (0000-0001-9129-7425), Xiao‐Bin Zhang (0000-0002-5155-8560, Soochow University), Guangya Zhang (0000-0002-2357-4854, Soochow University, corresponding author), Xiangdong Du (0000-0002-9263-0178, Soochow University, corresponding author) |
| Year | 2026 |
| Volume | 16 |
| Pages | 1697383-1697383 |
| Publication date | 2026-01-07 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Psychiatry (JOURNAL) |
| Journal identifiers | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Publisher | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2025.1697383 |
| PMID | 41573035 |
| OpenAlex | W7118238884 |
| Language | EN |
| References cited | 71 |
Our research indicates that neural cell adhesion molecule L1, integrin alpha-M, alpha-actinin-1, filamin-A and profilin-1 which are associated with cytoskeleton, synapse and immunity were preliminarily screened as candidate protein markers for schizophrenia. Moreover, mitogen-activated protein kinase signaling pathway may be related to the pathology of schizophrenia, and PI3K-Akt signaling pathway may be related to the efficacy and side effects of antipsychotic drugs
Antipsychotic · Cell adhesion · Cell adhesion molecule · Cell Signaling · Integrin · Proteomics · Schizophrenia (object-oriented programming · Signal transduction · Advanced Proteomics Techniques and Applications · Schizophrenia research and treatment · Tryptophan and brain disorders
| Highly cited | No |
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