Serine racemase deletion alters adolescent social behavior and whole-brain cFos activation
Bibliographic Data
| ID | 15519834 |
|---|---|
| Authors | Stephanie E Brown (0000-0003-2527-9223, McLean Hospital), Ziyi Wang (0000-0003-0922-7183, McLean Hospital), Emily L Newman (0000-0003-0978-1600, Harvard University), Elif Engin (0000-0002-1804-6811, McLean Hospital), Sabina Berretta (0000-0002-4057-7766, McLean Hospital), Darrick T Balu (0000-0003-3505-6832, Harvard University), Oluwarotimi Folorunso (0000-0001-9473-3587, Harvard University, corresponding author), Oluwarotimi O Folorunso |
| Year | 2024 |
| Volume | 15 |
| Pages | 1365231-1365231 |
| Publication date | 2024-06-24 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Psychiatry (JOURNAL) |
| Journal identifiers | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Publisher | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2024.1365231 |
| PMID | 38979499 |
| OpenAlex | W4399983472 |
| Language | EN |
| References cited | 57 |
These results suggest that NMDAR hypofunction - a potential biomarker for NDDs - can lead to generalized behavioral disinhibition in adolescence, potentially arising from disrupted communication between and within salience and default mode networks
Anxiety · Cognition · Developmental psychology · Disinhibition · Habituation · Psychiatry · Social anxiety · Social cognition · Social defeat · Amino Acid Enzymes and Metabolism · Epigenetics and DNA Methylation · Genetics and Neurodevelopmental Disorders · Neuroscience · Psychology
| Highly cited | No |
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