Association of SLC6A3 variants with treatment-resistant schizophrenia: A genetic association study of dopamine-related genes in schizophrenia

Masanobu Kogure; Nobuhisa Kanahara; Atsuhiro Miyazawa; Yuki Shiko; Ikuo Otsuka; Koichi Matsuyama; Masayuki Takase; Makoto Kimura; Hiroshi Kimura; Kiyomitsu Ota; Keita Idemoto; Masaki Tamura; Yasunori Oda; Taisuke Yoshida; Kenji Okazaki; Fumiaki Yamasaki; Yusuke Nakata; Yoshinori Watanabe; Tomihisa Niitsu; Akitoyo Hishimoto; Masaomi Iyo

doi:10.3389/fpsyt.2023.1334335

Association of SLC6A3 variants with treatment-resistant schizophrenia

A genetic association study of dopamine-related genes in schizophrenia

Bibliographic Data

ID	15519956
Authors	Masanobu Kogure (Chiba University), Nobuhisa Kanahara (0000-0001-8550-8003, Center for Forensic Mental Health, Chiba University, corresponding author), Atsuhiro Miyazawa (Kisarazu Hospital), Yuki Shiko (0000-0002-3959-9343, Chiba University Hospital), Ikuo Otsuka (0000-0002-2831-9158, Kobe University), Koichi Matsuyama (Chiba University), Masayuki Takase (0000-0002-4988-1908), Makoto Kimura (0000-0003-0868-5334, Kameda Medical Center), Hiroshi Kimura (0000-0001-6772-1863, Chiba University), Kiyomitsu Ota (Kisarazu Hospital), Keita Idemoto (0000-0002-7161-4275, Chiba University), Masaki Tamura (Chiba University), Yasunori Oda (0000-0002-4957-5847, Chiba University), Taisuke Yoshida (Kisarazu Hospital), Kenji Okazaki (0000-0001-5953-5526, Kobe University), Fumiaki Yamasaki (Chiba University), Yusuke Nakata (0009-0003-2816-3733, Chiba University), Yoshinori Watanabe (0000-0002-5488-4812, Tokyo Institute of Psychiatry), Tomihisa Niitsu (0000-0003-2713-700X, Chiba University), Akitoyo Hishimoto (0000-0001-9405-8235, Kobe University), Masaomi Iyo (0000-0002-5384-857X, Chiba University)
Year	2024
Volume	14
Pages	1334335-1334335
Publication date	2024-02-27
Open Access	Yes
Type	ARTICLE
Venue	Frontiers in Psychiatry (JOURNAL)
Journal identifiers	ISSN: 1664-0640 • E-ISSN: 1664-0640
Publisher	Frontiers Media (PUBLISHER • CH)
DOI	10.3389/fpsyt.2023.1334335
PMID	38476817
OpenAlex	W4392200367
Language	EN
References cited	6

The overall results suggest that ( i ) SLC6A3 could be involved in responsiveness to antipsychotic medication and ( ii ) genetic variants modulating brain DA levels may be related to the classification of TRS and non-TRS

Allele · Antipsychotic · Biology · Gene · Genotype · Psychiatry · Psychopathology · Schizophrenia (object-oriented programming · Bipolar Disorder and Treatment · Diabetes Treatment and Management · Medicine · Schizophrenia research and treatment · Genetics · Internal Medicine · Oncology

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