Executive Functioning in Chinese Patients With Obsessive Compulsive Disorder
Bibliographic Data
| ID | 15520205 |
|---|---|
| Authors | Huicong Ren (Xinxiang Medical University), Haibin Li (0000-0003-0815-594X, Fudan University), Jin Huang (0000-0002-2833-8041, Shanghai Jiao Tong University), Nan Zhang (0000-0002-8032-275X, Liaoning Normal University), Ruiqin Chen (University of Edinburgh), Wenjuan Liu (0000-0003-0572-5310, Zhongshan Hospital, corresponding author), Zhaohui Zhang (0000-0001-5376-5814, First Affiliated Hospital of Xinxiang Medical University, corresponding author), Chencheng Zhang (0000-0003-4472-4134, Shanghai Center for Brain Science and Brain-Inspired Technology, corresponding author) |
| Year | 2021 |
| Volume | 12 |
| Pages | 662449-662449 |
| Publication date | 2021-08-25 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Psychiatry (JOURNAL) |
| Journal identifiers | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Publisher | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2021.662449 |
| PMID | 34512409 |
| OpenAlex | W3195171343 |
| Language | EN |
| Citations received | 1 |
| References cited | 21 |
Introduction: Studies have shown that patients with obsessive compulsive disorder (OCD) often perform more poorly than healthy control (HC) participants on cognitive tasks involving executive functions. Most studies, however, have been performed in Western countries and societies, making it uncertain whether impaired executive functions can also be observed among non-Western patients with OCD. To address this gap in the literature, we evaluated several executive functions in Chinese patients with OCD and HCs. Methods: Participants included consisted of 46 Chinese patients with OCD (25 men, 21 women), ranging in age from 19 to 56 years, and 45 matched HCs without any self-reported lifetime psychiatric disorder. They all lived in Shanghai or the surrounding area. Five tests of the Cambridge Neuropsychological Test Automated Battery (CANTAB) were used to evaluate several executive functions (response inhibition, spatial working memory, planning, and cognitive flexibility) along with testing basic learning and visual recognition memory. Statistical tests using a Bonferroni-corrected significance level of p = 0.003 were performed to assess overall patient-control group differences in cognitive performance. Additionally, we explored performance differences between patients classified as having either relatively mild symptoms or severe symptoms based on the individual total scores on the Yale-Brown Obsessive-Compulsive Scale. Results: There were no significant performance differences between patients with OCD and HC in any of the cognitive tests. Similarly, cognitive performance of patients with relatively mild OCD symptoms did not differ significantly from that of patients with severe symptoms. Conclusions: These results do not seem to support the view that impaired executive functioning represents a basic cognitive and pathophysiological feature of Chinese patients with OCD. However, due to study limitations, additional research is required before this conclusion can be well accepted
Cambridge Neuropsychological Test Automated Battery · Cognition · Cognitive flexibility · Executive dysfunction · Executive functions · Neuropsychology · Psychiatry · Spatial memory · Working memory · Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes · Clinical Psychology · Eating Disorders and Behaviors · Medicine · Obsessive-Compulsive Spectrum Disorders · Psychology
| Citations per year | 1 |
|---|---|
| Citation span | 2025 - 2025 (1) |
| Highly cited | No |