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Gait Alterations in the Prediction of Metabolic Syndrome in Patients With Schizophrenia

A Pilot Study With Podosmart ® Insoles

Bibliographic Data

ID15520609
AuthorsDimitris Efthymiou (0000-0002-2941-4819, Aristotle University of Thessaloniki), Dimitrios Xipolias Zekakos, Evangelia Papatriantafyllou (International Hellenic University), Efthimis Ziagkas (Aristotle University of Thessaloniki), Alexandros M Petrelis (0000-0001-9156-4896), Alexandros N Petrelis, Εmilia Vassilopoulou (0000-0002-2665-5908, International Hellenic University, corresponding author)
Year2022
Volume13
Pages756600-756600
Publication date2022-01-27
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2022.756600
PMID35153872
OpenAlexW4210751000
LanguageEN
Citations received1
References cited55

The MPS group had significantly higher mean body mass index (BMI) and arterial blood pressure (BP) than the PS group. PODOSmart ® gait analysis recorded significant differences between groups in pronation-supination at Heel Off (HO), gaitline HO and gaitline Toe Off (TO). Multifactorial elastic net regression models demonstrated significant association with MetS of inflammatory markers, specific AP2 treatment, gender, age; BMI; BP and smoking (accuracy λ = 0.08), and in relation to gait parameters (accuracy λ = 0.750), the three pronation- supination variables, i.e., at HO, flat foot in (AP2 related) and TO, and propulsion speed. The gait parameters were at the edges of the model, thus indicating a more significant role of these parameters compared to the other clinical variables. Early diagnosis of MetS in patients with schizophrenia via identification of gait alterations can be a screening measure for serious cardiovascular complications related to psychosis and APs, to enable timely dietary intervention that can control the pro-inflammatory state and reduce oxidative stress

Blood pressure · Body mass index · Gait · Metabolic syndrome · Obesity · Oxidative stress · Physical medicine and rehabilitation · Physical therapy · Psychiatry · Psychosis · Schizophrenia (object-oriented programming · Adipokines, Inflammation, and Metabolic Diseases · Medicine · Schizophrenia research and treatment · Tryptophan and brain disorders · Internal Medicine

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  • The metabolic syndrome—a new worldwide definition

    Open Access•K G M M Alberti, K George MM Alberti et al.•The Lancet•2005

  • Association between the metabolic syndrome and its components and gait speed among U.S. adults aged 50 years and older

    Open Access•Catherine A Okoro, Yuna Zhong et al.•BMC Public Health•2006

  • Metabolic Syndrome in Psychotic Disorder Patients Treated With Oral and Long-Acting Injected Antipsychotics

    Open Access•Antonio Ventriglio, Ross J Baldessarini et al.•Frontiers in Psychiatry•2019

  • Monitoring and Treating Metabolic Abnormalities in Patients with Early Psychosis Initiated on Antipsychotic Medications

    Open Access•Kevin M Bozymski, Jessica Whitten et al.•Community Mental Health Journal•2017

Citations per year0.5
Citation span2024 - 2024 (1)
Highly citedNo

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