The Association Between Antipsychotics and Weight Gain and the Potential Role of Metformin Concomitant Use

A Retrospective Cohort Study

Bibliographic Data

ID15520804
AuthorsAlqassem Y Hakami (0000-0003-2477-1339, King Saud bin Abdulaziz University for Health Sciences, corresponding author), Razaz Felemban (0009-0002-8792-7572, King Saud bin Abdulaziz University for Health Sciences), Rami Ghazi Ahmad (King Abdullah International Medical Research Center), Abdulrahman Alsamadani (King Saud bin Abdulaziz University for Health Sciences), Abdulrahman H Al-Samadani, Hassan K Salamatullah (0009-0006-7860-4711, King Saud bin Abdulaziz University for Health Sciences), Jamil M Baljoon (King Saud bin Abdulaziz University for Health Sciences), Loay J Alghamdi (King Saud bin Abdulaziz University for Health Sciences), Mostafa H Ramadani Sindi (King Saud bin Abdulaziz University for Health Sciences), Mohamed Eldigire Ahmed (0000-0003-0326-7926, King Saud bin Abdulaziz University for Health Sciences)
Year2022
Volume13
Pages914165-914165
Publication date2022-05-24
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2022.914165
PMID35686187
OpenAlexW4285740374
LanguageEN
References cited26

Statistical analysis revealed that patients on antipsychotics alone experienced weight gain, whereas the concomitant use of metformin showed reduction in the weight gain tendency. Thus, study outcomes indicate that concomitant use of metformin with antipsychotics might significantly reduce the AIWG

Antipsychotic · Body weight · Cohort · Cohort study · Concomitant · Insulin · Medical record · Metformin · Obesity · Population · Psychiatry · Retrospective cohort study · Schizophrenia (object-oriented programming · Weight gain · Diabetes Treatment and Management · Medicine · Pharmacology and Obesity Treatment · Schizophrenia research and treatment · Internal Medicine · Pediatrics

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