Radiation Risk Analysis of Neuropsychiatric Disorders in Ukrainian Chornobyl Catastrophe Liquidators

Bibliographic Data

ID15520923
AuthorsK Loganovsky (0000-0002-0680-8882, National Academy of Medical Sciences of Ukraine, corresponding author), Konstantyn N Loganovsky, Sergii Masiuk (0000-0002-5123-9674, National Academy of Medical Sciences of Ukraine), Sergii V Masiuk, V Buzunov (National Academy of Medical Sciences of Ukraine), Vladimir A Buzunov, Donatella Marazziti (0000-0002-4021-5829, University of Pisa), Yuliya S Voychulene (National Academy of Medical Sciences of Ukraine)
Year2020
Volume11
Pages553420-553420
Publication date2020-11-17
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2020.553420
PMID33312134
OpenAlexW3105908104
LanguageEN
References cited46

Goal: To explore the possible impact of ionizing radiation in the pathophysiology of neuropsychiatric disorders amongst clean-up workers of the Chornobyl catastrophe (liquidators). Design, object, and methods: Retrospective-prospective study (1987-2015) of liquidators from the State Register of Ukraine (SRU) with radiation doses records and Clinical-Epidemiological Register (CER) of the State Institution ≪National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine≫ (NRCRM). Moreover, cohort and cross-sectional studies of the randomized sample of liquidators from the CER (exposed group, 198 subjects) were examined. Internal control group included the liquidators irradiated in doses Results: Exposed group vs. control group showed cognitive disorders in 99 (50.0%) vs. 20 (18.1%), ( P = 0.04); affective disorders in 96 (48.3%) vs. 36 (32.7%) ( P = 0.007), and stress-related disorders in 115 (58.4%) vs. 8 (7.3%) ( P P P = 0.009). Relative risks (RR) and 95% confidential intervals (95%CI) of Incidence of some neuropsychiatric disorders in liquidators of 1986-1987 related to internal control (doses Pv -2 (95% CI 1.06-7.15). Conclusions: Liquidators have an excess of cognitive, affective, and stress-related disorders. The risk of diseases rises with radiation dose. Radiation risks are revealed for organic psychoses, non-psychotic organic brain damage, acute and chronic cerebrovascular pathology

Cohort · Confidence interval · Incidence (geometry · Psychiatry · Relative risk · Medicine · Radiation Dose and Imaging · Epidemiology · Internal Medicine

Tools

Open DOIOpen Access