Aberrant functional connectivity of the dorsolateral prefrontal cortex-nucleus accumbens during naturalistic stimulation in adolescent major depressive disorder
Bibliographic Data
| ID | 15521950 |
|---|---|
| Authors | Yingzhe Zhao (Beijing Anding Hospital), Zhuo Xi (Harbin Medical University), Zhenxiang Zang (0000-0002-6865-054X), Z P ZANG (Beijing Anding Hospital), Zhi Yang (0000-0002-2341-5394, Beijing Anding Hospital), Jing Liu (0000-0002-0965-0320, Beijing Anding Hospital, corresponding author) |
| Year | 2026 |
| Volume | 16 |
| Pages | 1705969-1705969 |
| Publication date | 2026-01-05 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Psychiatry (JOURNAL) |
| Journal identifiers | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Publisher | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2025.1705969 |
| PMID | 41561996 |
| OpenAlex | W7118200853 |
| Language | EN |
| References cited | 37 |
These findings suggest that DLPFC-NAc hyperconnectivity is a neural substrate of MDD in adolescents and may preferentially contribute to anxiety-related or somatization-related symptomatology rather than depressive mood or sleep disturbance
Dorsolateral prefrontal cortex · Functional connectivity · Major depressive disorder · Mood · Mood disorders · Neural substrate · Nucleus accumbens · Prefrontal cortex · Schizophrenia (object-oriented programming · Functional Brain Connectivity Studies · Mental Health Research Topics · Transcranial Magnetic Stimulation Studies
Large-Scale Network Dysfunction in Major Depressive Disorder
Severity classification on the Hamilton depression rating scale
Adolescence as a pivotal period for emotion regulation development
Alterations of Static and Dynamic Functional Connectivity of the Nucleus Accumbens in Patients With Major Depressive Disorder
Antidepressant Treatment-Induced State-Dependent Reconfiguration of Emotion Regulation Networks in Major Depressive Disorder
| Citation velocity | historical |
|---|---|
| Highly cited | No |