Systematic Review of Parameters of Stimulation, Clinical Trial Design Characteristics, and Motor Outcomes in Non-Invasive Brain Stimulation in Stroke
Bibliographic Data
| ID | 15521986 |
|---|---|
| Authors | Bamidele O Adeyemo (Spaulding Rehabilitation Hospital, corresponding author), Marcel Simis (0000-0003-1656-9659, Spaulding Rehabilitation Hospital), Debora Duarte Macea (Spaulding Rehabilitation Hospital), Felipe Fregni (0000-0001-9359-8643, Spaulding Rehabilitation Hospital) |
| Year | 2012 |
| Volume | 3 |
| Publication date | 2012-01-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Psychiatry (JOURNAL) |
| Journal identifiers | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Publisher | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2012.00088 |
| PMID | 23162477 |
| PMCID | PMC3495265 |
| OpenAlex | W2127849837 |
| Language | EN |
| Citations received | 2 |
| References cited | 2 |
Introduction: Repetitive Transcranial Magnetic Stimulation (rTMS) and Transcranial Direct Current Stimulation are two powerful non-invasive neuromodulatory therapies that have the potential to alter and evaluate the integrity of the corticospinal tract. Moreover, recent evidence has shown that brain stimulation might be beneficial in stroke recovery. Therefore, investigating and investing in innovative therapies that may improve neurorehabilitative stroke recovery are next steps in research and development. Methods: This article presents an up-to-date systematic review of the treatment effects of rTMS and tDCS on motor function. A literary search was conducted, utilizing search terms “stroke” and “transcranial stimulation”. Items were excluded if they failed to: (1) include stroke patients, (2) study motor outcomes, or (3) include rTMS/tDCS as treatments. Other exclusions included: (1) reviews, editorials, and letters, (2) animal or pediatric populations, (3) case reports or sample sizes < or = 2 patients, and (4) primary outcomes of dysphagia, dysarthria, neglect, or swallowing. Results: Investigation of PubMed English Database prior to 01/01/2012 produced 695 applicable results. Studies were excluded based on the aforementioned criteria, resulting in 50 remaining studies. They included 1314 participants (1282 stroke patients and 32 healthy subjects) evaluated by motor function pre- and post- tDCS or rTMS. Heterogeneity among studies’ motor assessments was high and could not be accounted for by individual comparison. Pooled effect sizes for the impact of post-treatment improvement revealed consistently demonstrable improvements after tDCS and rTMS therapeutic stimulation. Most studies provided limited follow-up for long-term effects. Conclusions: It is apparent from the available studies that noninvasive stimulation may enhance motor recovery and may lead to clinically-meaningful functional improvements in the stroke population
Audiology · Brain stimulation · Corticospinal tract · Dysarthria · Dysphagia · Magnetic resonance imaging · Neurorehabilitation · Physical medicine and rehabilitation · Physical therapy · Stimulation · Stroke (engine · Stroke recovery · Swallowing · Transcranial Direct Current Stimulation · Transcranial magnetic stimulation · Medicine · Muscle activation and electromyography studies · Neuroscience · Psychology · Stroke Rehabilitation and Recovery · Transcranial Magnetic Stimulation Studies · Rehabilitation · Surgery
| Citations per year | 0.15 |
|---|---|
| Citation span | 2013 - 2021 (9) |
| Highly cited | No |