Relationship between reduced serum ceruloplasmin levels and executive dysfunction in hospitalized schizophrenia patients
Bibliographic Data
| ID | 15522116 |
|---|---|
| Authors | Dan Kuang (0000-0002-0208-0812, Shaoxing People's Hospital), Hongkai Wei (0009-0001-3004-3218, Jining Traditional Chinese Medicine Hospital), Wei Qin (0000-0002-9199-966X, Shandong Mental Health Center, corresponding author) |
| Year | 2025 |
| Volume | 16 |
| Pages | 1618147-1618147 |
| Publication date | 2025-08-14 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Psychiatry (JOURNAL) |
| Journal identifiers | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Publisher | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2025.1618147 |
| PMID | 40896216 |
| OpenAlex | W4413970583 |
| Language | EN |
| References cited | 34 |
Based on the existing evidence of widespread cognitive impairment in schizophrenia patients, this study delves deeper into its potential causes. We found that regardless of whether schizophrenia patients had normal or low serum ceruloplasmin (CP) levels, their executive function was significantly lower than that of healthy individuals. Furthermore, a correlation analysis showed a significant link between CP levels and executive dysfunction in schizophrenia patients with decreased CP levels. Our study suggests that low CP levels may aggravate executive dysfunction, indicating that CP deficiency might be a biological marker of executive dysfunction in schizophrenia
Ceruloplasmin · Cognition · Executive dysfunction · Executive functions · Neuropsychology · Psychiatry · Schizophrenia (object-oriented programming · Clinical Psychology · Magnesium in Health and Disease · Medicine · Sodium Intake and Health · Trace Elements in Health · Internal Medicine
| Citation velocity | historical |
|---|---|
| Highly cited | No |