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Relationship between reduced serum ceruloplasmin levels and executive dysfunction in hospitalized schizophrenia patients

Bibliographic Data

ID15522116
AuthorsDan Kuang (0000-0002-0208-0812, Shaoxing People's Hospital), Hongkai Wei (0009-0001-3004-3218, Jining Traditional Chinese Medicine Hospital), Wei Qin (0000-0002-9199-966X, Shandong Mental Health Center, corresponding author)
Year2025
Volume16
Pages1618147-1618147
Publication date2025-08-14
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2025.1618147
PMID40896216
OpenAlexW4413970583
LanguageEN
References cited34

Based on the existing evidence of widespread cognitive impairment in schizophrenia patients, this study delves deeper into its potential causes. We found that regardless of whether schizophrenia patients had normal or low serum ceruloplasmin (CP) levels, their executive function was significantly lower than that of healthy individuals. Furthermore, a correlation analysis showed a significant link between CP levels and executive dysfunction in schizophrenia patients with decreased CP levels. Our study suggests that low CP levels may aggravate executive dysfunction, indicating that CP deficiency might be a biological marker of executive dysfunction in schizophrenia

Ceruloplasmin · Cognition · Executive dysfunction · Executive functions · Neuropsychology · Psychiatry · Schizophrenia (object-oriented programming · Clinical Psychology · Magnesium in Health and Disease · Medicine · Sodium Intake and Health · Trace Elements in Health · Internal Medicine

Citation velocityhistorical
Highly citedNo

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