Evaluating the rational use of antidepressant in older patients

A comprehensive analysis of its association with cognitive impairment

Dados Bibliográficos

ID15522342
AutoresMaría Gil‐Peinado (0000-0001-5593-1484, Universitat de València), María Gil-Peinado, Juan Pardo (0000-0001-9662-0850, Universidad Cardenal Herrera CEU), Mar García-Zamora (0009-0004-4952-0258, Valencia Catholic University Saint Vincent Martyr), Gonzalo Miguel Adsuar-Meseguer (Valencia Catholic University Saint Vincent Martyr), José Sendra‐Lillo (0000-0002-2669-5862, Universitat de València), José Sendra-Lillo, Lucrecia Moreno (0000-0002-9456-9649, Universidad Cardenal Herrera CEU, autor correspondente)
Ano2025
Volume16
Páginas1624989-1624989
Data de publicação2025-10-20
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoFrontiers in Psychiatry (JOURNAL)
Identificadores do periódicoISSN: 1664-0640 • E-ISSN: 1664-0640
EditoraFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2025.1624989
PMID41190297
OpenAlexW4415363057
IdiomaEN
Referências citadas56

Despite their widespread use, antidepressants raise concerns regarding their efficacy and safety, particularly due to the risk of exacerbating CI. This study underscores the need for careful management of antidepressant therapy and suggests exploring alternatives such as vortioxetine, which may offer cognitive benefits. Enhanced interprofessional collaboration and regular cognitive evaluations are recommended to improve patient outcomes and ensure the rational use of antidepressants

Antidepressant · Association (psychology · Cognition · Cognitive impairment · Depression (economics · MEDLINE · Cardiac Health and Mental Health · Dementia and Cognitive Impairment Research · Intensive Care Unit Cognitive Disorders