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Global, regional, and national burden of schizophrenia

Epidemiological trends, decomposition, joinpoint analysis, and projections to 2036 based on GBD 2021

Bibliographic Data

ID15522508
AuthorsWanting Zhou (0000-0002-1477-3739, Riverside Hospital of Guangxi Zhuang Autonomous Region), Jiujie He (Guangxi University of Chinese Medicine), Lishuo Wu (Riverside Hospital of Guangxi Zhuang Autonomous Region), Liwen Wang (0000-0003-0285-0079, Riverside Hospital of Guangxi Zhuang Autonomous Region), Kejun Wu (0000-0003-3948-1924, Guangxi Medical University), Zongyu Li (0000-0002-9015-1384, Guangxi Medical University), Gang Chen (0000-0002-8385-5965, Guangxi Medical University), Donglian Li (0009-0005-7850-2005, Riverside Hospital of Guangxi Zhuang Autonomous Region), Yi Yang (0000-0002-9729-8522, Riverside Hospital of Guangxi Zhuang Autonomous Region), Jian Dai (0000-0002-8906-3360, Department of Clinical Psychology, Jiangbin Hospital of Guangxi Zhuang Autonomous Region, corresponding author)
Year2026
Volume17
Pages1702808-1702808
Publication date2026-02-12
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2026.1702808
PMID41767144
OpenAlexW7128713861
LanguageEN
References cited56

While schizophrenia currently exerts a disproportionately higher burden on young and middle-aged males, our projections indicate a notable epidemiological shift, with females expected to experience a steeper rise in incidence, prevalence, and DALYs over the next 15 years. This emerging female-centric trend contrasts sharply with the current male-dominated profile, underscoring the urgent need for sex-responsive mental health strategies

Burden of disease · Epidemiological transition · Mental health · Public health · Schizophrenia (object-oriented programming · Mental Health Treatment and Access · Psychopathy, Forensic Psychiatry, Sexual Offending · Schizophrenia research and treatment · Epidemiology

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