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Metabolite-disease interaction prediction based on logistic matrix factorization and local neighborhood constraints

Bibliographic Data

ID15522880
AuthorsYongbiao Zhao (0000-0002-4090-9185, Central China Normal University), Yuanyuan Ma (0000-0002-1090-4551, Hubei University of Arts and Science, corresponding author), Qilin Zhang (0000-0003-2687-5369, Hubei University of Arts and Science)
Year2023
Volume14
Pages1149947-1149947
Publication date2023-06-05
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2023.1149947
PMID37342171
OpenAlexW4379467780
LanguageEN
References cited21

The proposed LMFLNC method can well preserve the geometrical structure of original data and can thus effectively predict the underlying associations between metabolites and diseases. The experimental results show its effectiveness in metabolite-disease interaction prediction

Biology · Computational biology · Disease · Matrix decomposition · Metabolite · Non-negative matrix factorization · Physics · Similarity (geometry · Bioinformatics and Genomic Networks · Computer Science · Machine Learning in Bioinformatics · Medicine · Metabolomics and Mass Spectrometry Studies · Artificial Intelligence · Biochemistry · Internal Medicine

Highly citedNo

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