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Mendelian randomization analyses for the causal relationship between early age at first sexual intercourse, early age at first live birth, and postpartum depression in pregnant women

Bibliographic Data

ID15523131
AuthorsXuemin Zhao (0000-0001-9952-2236, Chengde Medical University, corresponding author), Linfei Liu (Sericultural Research Institute)
Year2024
Volume15
Pages1287934-1287934
Publication date2024-04-08
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2024.1287934
PMID38651010
OpenAlexW4394575444
LanguageEN
Citations received2
References cited41

MR studies based on GWAS data revealed that both AFS (OR = 0.4, P 0.001) and AFB (OR = 0.38, P 0.001) were negatively correlated with the risk of PPD. Early AFS and early AFB should be studied as possible risk factors for PPD in the future. Public health departments should attach importance to sex education for young girls. The results of our TSMR should be verified by high-quality prospective epidemiological studies in the future

Biology · Depression (economics · Genotype · Mendelian randomization · Obstetrics · Population · Postpartum depression · Pregnancy · Psychiatry · Sexual intercourse · Adolescent Sexual and Reproductive Health · Birth, Development, and Health · Clinical Psychology · Maternal Mental Health During Pregnancy and Postpartum · Medicine · Psychology · Genetics

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Citations per year1
Citation span2024 - 2025 (2)
Highly citedNo

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