Altered Heart Rate Variability in Patients With Schizophrenia During an Autonomic Nervous Test
Bibliographic Data
| ID | 15523446 |
|---|---|
| Authors | Ya Liu (0000-0001-5106-8708, South China University of Technology), Yuanyuan Huang (0000-0001-7752-4054, Guangzhou Medical University), Jing Zhou (0009-0007-8795-5916, South China University of Technology), Jing Li Zhou (0000-0002-8186-0787), Guixiang Li (0000-0002-8730-0713, Guangdong Academy of Sciences), Jun Chen (0000-0002-3850-4875, Guangdong Academy of Sciences), Zhiming Xiang (0000-0003-2037-6446, Panyu District Central Hospital, corresponding author), Fengchun Wu (0000-0003-2817-2341, Guangzhou Psychiatric Hospital, corresponding author), Kai Wu (0000-0003-4684-9758, South China University of Technology, corresponding author) |
| Year | 2021 |
| Volume | 12 |
| Pages | 626991-626991 |
| Publication date | 2021-03-30 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Psychiatry (JOURNAL) |
| Journal identifiers | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Publisher | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2021.626991 |
| PMID | 33912081 |
| OpenAlex | W3148383665 |
| Language | EN |
| References cited | 48 |
Reduced heart rate variability (HRV) and dysfunction of the autonomic nervous system (ANS) have been observed in schizophrenia patients. HRV parameters of schizophrenia patients in the resting state have been well-documented; however, these parameters of schizophrenia patients who experience continuous psychophysiological stress remain unclear. The objective of this study was to systematically explore the linear and nonlinear HRV parameters between schizophrenia patients and normal controls and to detect the adaptive capabilities of HRV of schizophrenia patients during the stimulation tests of autonomic nervous system. Forty-five schizophrenia patients and forty-five normal controls, matched for age, sex and body mass index, completed a 14 min ANS test. Thirteen linear and nonlinear HRV parameters of all subjects under the ANS test were computed and statistically analyzed between groups and between sessions. The STROBE checklist was adhered to in this study. All time-domain HRV features in the ANS test were significantly different between schizophrenia patients and normal controls ( p p < 0.001). In addition, the normal controls, not schizophrenia patients, showed significant differences between the recovery and stress states in the parameters of low frequency, high frequency, and nonlinear dynamics. Schizophrenia patients showed autonomic dysfunction of the heart in a series of stimulation tests of the autonomic nervous system and could not regain normal physiological functions after stress cessation. Our findings revealed that the dynamic parameters of HRV in psychophysiological stress are sensitive and practical for a diagnosis of schizophrenia
Autonomic nervous system · Blood pressure · Cardiology · Heart rate · Heart rate variability · Psychiatry · Psychosis · Schizophrenia (object-oriented programming · EEG and Brain-Computer Interfaces · Heart Rate Variability and Autonomic Control · Medicine · Non-Invasive Vital Sign Monitoring · Psychology · Internal Medicine
| Citation velocity | historical |
|---|---|
| Highly cited | No |