Examining putamen resting-state connectivity markers of suicide attempt history in depressed adolescents
Bibliographic Data
| ID | 15523514 |
|---|---|
| Authors | Olga Tymofiyeva (0000-0003-2589-1041, University of California, San Francisco, corresponding author), Tiffany C Ho (0000-0002-4500-6364, University of California, Los Angeles), Colm G Connolly (0000-0002-4051-3682, Florida State University), Sasha Gorrell (0000-0002-8861-8547, University of California, San Francisco), Ryan Rampersaud (0000-0003-4718-0267, University of California, San Francisco), Sabrina M Darrow (0000-0002-5639-0285, University of California, San Francisco), Jeffrey E Max (0000-0002-6566-1585, Rady Children's Hospital-San Diego), Tony T Yang (0000-0003-2727-9438, University of California, San Francisco) |
| Year | 2024 |
| Volume | 15 |
| Pages | 1364271-1364271 |
| Publication date | 2024-06-06 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Psychiatry (JOURNAL) |
| Journal identifiers | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Publisher | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2024.1364271 |
| PMID | 38903634 |
| OpenAlex | W4399524030 |
| Language | EN |
| Citations received | 1 |
| References cited | 64 |
The results align with recent adult literature and have interesting theoretical and clinical implications. A possible interpretation of the results is a mismatch of the serotonin transport to putamen and to the supplementary motor area and the resulting reduced functional connectivity between the two areas in adolescents with attempt history. The obtained results can be used to enhance the diathesis-stress model and the Emotional paiN and social Disconnect (END) model of adolescent suicidality by adding the putamen. We also speculate that connectivity between putamen and the supplementary motor area may in the future be used as a valuable biomarker of treatment efficacy and possibly prediction of treatment outcome
Depression (economics · Injury prevention · Poison control · Psychiatry · Putamen · Serotonergic · Serotonin · Striatum · Suicidal ideation · Ventral striatum · Advanced Neuroimaging Techniques and Applications · Clinical Psychology · Functional Brain Connectivity Studies · Medicine · Mental Health Research Topics · Neuroscience · Psychology · Internal Medicine
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| Citations per year | 1 |
|---|---|
| Citation span | 2025 - 2025 (1) |
| Highly cited | No |