Ketamine-assisted psychotherapy in adolescents with multiple psychiatric diagnoses

Datos Bibliográficos

ID15523865
AutoresPhilip E Wolfson (0000-0003-0867-0861, Pine Street Foundation, autor de correspondencia), Julane Andries (EnZinc (United States)), Daniel Ahlers (0000-0002-9751-626X, Pine Street Foundation), Melissa Whippo (EnZinc (United States))
Año2023
Volumen14
Páginas1141988-1141988
Fecha de publicación2023-03-30
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaFrontiers in Psychiatry (JOURNAL)
Identificadores de la revistaISSN: 1664-0640 • E-ISSN: 1664-0640
EditorialFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2023.1141988
PMID37065886
OpenAlexW4361272495
IdiomaEN
Citas recibidas3
Referencias citadas60

Ketamine-assisted psychotherapy is a promising new treatment for a variety of mental disorders of adolescence. There is currently an adolescent mental health crisis, with a high prevalence of disorders, diagnostic complexity, and many adolescents failing to respond to conventional treatments. While there is strong evidence for the use of ketamine in adults for a variety of treatment-refractory mental illnesses, research in adolescents is in its early stages. Ketamine-assisted psychotherapy (KAP) has been described in adults with promising results and here we present the first published cases of the use of KAP in adolescents. The four cases include adolescents aged 14-19 at the initiation of treatment, each with a variety of comorbid diagnoses including treatment-resistant depression, bipolar disorder, eating disorders, anxiety, panic, and trauma-related symptoms. They each initially received sublingual ketamine, followed by sessions with intramuscular ketamine. Their courses varied, but each had symptomatic and functional improvements, and the treatment was well-tolerated. Subjective patient reports are included. Rapid resolution of symptomatology and suffering often occurs within months as the result of the application of KAP to adolescent psychiatric care but is not inevitable. Family involvement in the treatment process appears to be essential to success. The development of this modality may have a singularly positive impact that will expand the psychiatric toolbox and its healing potency

Anxiety · Depression (economics · Ketamine · Mental health · Panic disorder · Psychiatry · Bipolar Disorder and Treatment · Clinical Psychology · Medicine · Psychology · Treatment of Major Depression · Tryptophan and brain disorders