Abnormality of Resting-State Functional Connectivity in Major Depressive Disorder
A Study With Whole-Head Near-Infrared Spectroscopy
Bibliographic Data
| ID | 15524377 |
|---|---|
| Authors | Eisuke Sakakibara (0000-0002-6392-8450, The University of Tokyo, corresponding author), Yoshihiro Satomura (0000-0002-2495-6782, The University of Tokyo), Jun Matsuoka (0000-0002-0141-2504, The University of Tokyo), Shinsuke Koike (0000-0002-3375-236X, The University of Tokyo), Naohiro Okada (0000-0002-8338-2758, The University of Tokyo), Hanako Sakurada (The University of Tokyo), Mika Yamagishi (The University of Tokyo), Norito Kawakami (0000-0003-1080-2720, The University of Tokyo), Kazutaka Kasai (0000-0002-4443-4535, The University of Tokyo), Kiyoto Kasai |
| Year | 2021 |
| Volume | 12 |
| Pages | 664859-664859 |
| Publication date | 2021-04-29 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Psychiatry (JOURNAL) |
| Journal identifiers | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Publisher | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2021.664859 |
| PMID | 33995150 |
| OpenAlex | W3159918848 |
| Language | EN |
| Citations received | 3 |
| References cited | 39 |
Near-infrared spectroscopy (NIRS) is a functional neuroimaging modality that has advantages in clinical usage. Previous functional magnetic resonance imaging (fMRI) studies have found that the resting-state functional connectivity (RSFC) of the default mode network (DMN) is increased, while the RSFC of the cognitive control network (CCN) is reduced in patients with major depressive disorder (MDD) compared with healthy controls. This study tested whether the NIRS-based RSFC measurements can detect the abnormalities in RSFC that have been associated with MDD in previous fMRI studies. We measured 8 min of resting-state brain activity in 34 individuals with MDD and 78 age- and gender-matched healthy controls using a whole-head NIRS system. We applied a previously established partial correlation analysis for estimating RSFCs between the 17 cortical regions. We found that MDD patients had a lower RSFC between the left dorsolateral prefrontal cortex and the parietal lobe that comprise the CCN, and a higher RSFC between the right orbitofrontal cortex and ventrolateral prefrontal cortex, compared to those in healthy controls. The RSFC strength of the left CCN was negatively correlated with the severity of depressive symptoms and the dose of antipsychotic medication and positively correlated with the level of social functioning. The results of this study suggest that NIRS-based measurements of RSFCs have potential clinical applications
Anterior cingulate cortex · Cognition · Default mode network · Dorsolateral prefrontal cortex · Functional magnetic resonance imaging · Functional near-infrared spectroscopy · Major depressive disorder · Neuroimaging · Orbitofrontal cortex · Prefrontal cortex · Resting state fMRI · Functional Brain Connectivity Studies · Heart Rate Variability and Autonomic Control · Medicine · Neuroscience · Optical Imaging and Spectroscopy Techniques · Psychology
The impact of anxiety on the cognitive function of informal Parkinson’s disease caregiver
Altered resting-state prefrontal activity and network topology in adolescents with depression
The fNirs evaluation of frontal and temporal lobe cortical activation in Chinese first-episode medication-naïve and recurrent depression during a verbal fluency task
Large-Scale Network Dysfunction in Major Depressive Disorder
Functional connectivity in the motor cortex of resting human brain using echo‐planar mri
The World Mental Health (WMH) Survey Initiative version of the World Health Organization (WHO) Composite International Diagnostic Interview (CIDI)
G*Power 3
A Rating Scale for Depression
Harnessing reliability for neuroscience research
| Unique citing works | 3 |
|---|---|
| Citations per year | 0.75 |
| Citation span | 2022 - 2026 (5) |
| Citation velocity | current |
| Highly cited | No |
| Citation types | Neutral: 3 |