The Impact of Target Frequency on Intra-Individual Variability in Euthymic Bipolar Disorder
A Comparison of Two Sustained Attention Tasks
Bibliographic Data
| ID | 15524463 |
|---|---|
| Authors | Rachel Moss (0000-0002-7210-439X, The Neurosciences Foundation), R A Moss (0000-0003-4634-2367, The Neurosciences Foundation), Andreas Finkelmeyer (0000-0001-7491-5113, The Neurosciences Foundation), Lucy J Robinson (0000-0001-5838-8384, Cumbria Northumberland Tyne and Wear NHS Foundation Trust), Jill M Thompson (The Neurosciences Foundation), Stuart Watson (0000-0001-7228-3490, The Neurosciences Foundation), I Nicol Ferrier (0000-0002-1800-1648, Cumbria Northumberland Tyne and Wear NHS Foundation Trust), Peter Gallagher (0000-0002-9808-7460, The Neurosciences Foundation, corresponding author) |
| Year | 2016 |
| Volume | 7 |
| Pages | 106-106 |
| Publication date | 2016-06-16 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Psychiatry (JOURNAL) |
| Journal identifiers | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Publisher | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2016.00106 |
| PMID | 27378954 |
| OpenAlex | W2429613150 |
| Language | EN |
| References cited | 66 |
Greater intra-individual variability (IIV) in reaction time (RT) on a sustained attention task has been reported in patients with bipolar disorder (BD) compared with healthy controls. However, it is unclear whether IIV is task specific, or whether it represents general cross-task impairment in BD. This study aimed to investigate whether IIV occurs in sustained attention tasks with different parameters. Twenty-two patients with BD (currently euthymic) and 17 controls completed two sustained attention tasks on different occasions: a low target frequency (~20%) Vigil continuous performance test (CPT) and a high target frequency (~70%) CPT version A-X (CPT-AX). Variability measures (individual standard deviation and coefficient of variation) were calculated per participant, and ex-Gaussian modeling was also applied. This was supplemented by Vincentile analysis to characterize RT distributions. Results indicated that participants (patients and controls) were generally slower and more variable when completing the Vigil CPT compared with CPT-AX. Significant group differences were also observed in the Vigil CPT, with euthymic BD patients being more variable than controls. This result suggests that IIV in BD demonstrates some degree of task specificity. Further research should incorporate analysis of additional RT distributional models (drift diffusion and fast Fourier transform) to fully characterize the pattern of IIV in BD, as well as its relationship to cognitive processes
Analysis of variance · Audiology · Bipolar disorder · Cognition · Developmental psychology · Psychiatry · Task (project management · Vigil · Adolescent and Pediatric Healthcare · Bipolar Disorder and Treatment · Medicine · Mental Health Research Topics · Psychology · Internal Medicine
A continuous performance test of brain damage.
Effective Analysis of Reaction Time Data
The Endophenotype Concept in Psychiatry
The Diffusion Decision Model
A Rating Scale for Mania
Beck Depression Inventory–II
A Rating Scale for Depression
Variability in Reaction Time Performance of Younger and Older Adults
Analysis of response time distributions
| Citation velocity | historical |
|---|---|
| Highly cited | No |