Early Life Stress in Depressive Patients
HPA Axis Response to GR and MR Agonist
Bibliographic Data
| ID | 15524851 |
|---|---|
| Authors | Cristiane von Werne Baes (0000-0001-5361-9091, Universidade de São Paulo), Camila Maria Severi Martins (Universidade de São Paulo), Sandra Márcia de Carvalho Tofoli (Universidade de São Paulo), Mario F Juruena (0000-0001-8558-3396, Universidade de São Paulo, corresponding author) |
| Year | 2014 |
| Volume | 5 |
| Pages | 2-2 |
| Publication date | 2014-01-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Psychiatry (JOURNAL) |
| Journal identifiers | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Publisher | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2014.00002 |
| PMID | 24478730 |
| PMCID | PMC3900767 |
| OpenAlex | W2022369429 |
| Language | EN |
| Citations received | 1 |
| References cited | 17 |
Our findings indicate that MR activity is impaired in depressed patients compared with controls. Furthermore, in spite of the previous limitations described, in depressed patients with ELS, there was suppression by MR agonist, indicating that patients with ELS are sensitive to MR agonists. In contrast with depressed patients without ELS, we find suppression after both MR and GR agonist. These data suggested that in ELS an imbalance exists between MR and GR with MR dysfunction
Agonist · Hydrocortisone · Inverse agonist · Placebo · Receptor · Birth, Development, and Health · Hormonal Regulation and Hypertension · Medicine · Psychology · Stress Responses and Cortisol · Endocrinology · Internal Medicine
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Acute and Longer-Term Outcomes in Depressed Outpatients Requiring One or Several Treatment Steps
Free Cortisol Levels after Awakening
Stress and the brain
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Development and validation of a brief screening version of the Childhood Trauma Questionnaire
A Rating Scale for Depression
Depression and Hypothalamic-Pituitary-Adrenal Activation
Tradução e validação de conteúdo da versão em português do Childhood Trauma Questionnaire
| Citations per year | 0.13 |
|---|---|
| Citation span | 2018 - 2018 (1) |
| Highly cited | No |