Temporal atrophy together with verbal encoding impairment is highly predictive for cognitive decline in typical Alzheimer’s dementia – a retrospective follow-up study

Bibliographic Data

ID15525635
AuthorsBurak Doganyigit (Universität Innsbruck), Michaela Defrancesco (0000-0001-9613-9485, Universität Innsbruck, corresponding author), Timo Schurr (0000-0002-6757-7862, Innsbruck Medical University), Ruth Steiger (0000-0002-6905-9575, Universität Innsbruck), Elke R Gizewski (0000-0001-6859-8377, Innsbruck Medical University), Stephanie Mangesius (0000-0001-5790-2724, Universität Innsbruck), Malik Galijašević (0000-0001-6577-0784, Universität Innsbruck), Alex Hofer (0000-0002-5834-4258, Innsbruck Medical University), Noora Tuovinen (0000-0002-8835-5281, Universität Innsbruck)
Year2024
Volume15
Pages1485620-1485620
Publication date2024-11-19
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2024.1485620
PMID39628497
OpenAlexW4404509567
LanguageEN
References cited52

Our results show that temporal atrophy together with deficits in the encoding of verbal material, rather than in immediate or delayed recall, is highly predictive for rapid cognitive decline in patients with mild to moderate amnestic/typical ADD. These findings point to the relevance of combining detailed cognitive and automated structural imaging analyses to predict clinical progression in patients with ADD

Alzheimer's disease · Atrophy · Audiology · Cognition · Cognitive decline · Cognitive impairment · Dementia · Disease · Pathology · Psychiatry · Alzheimer's disease research and treatments · Clinical Psychology · Dementia and Cognitive Impairment Research · Medicine · Neurological Disease Mechanisms and Treatments · Psychology

Tools

Open DOIOpen Access