The role of hypothyroidism in the resilience against depressive episodes during covid pandemic in a cohort of old adults

Bibliographic Data

ID15525828
AuthorsAlessandra Perra (0000-0001-5791-1655, Popular University of Cesar, corresponding author), Massimo Tusconi (0000-0002-9155-4740, Klinik für Psychosomatik), Elisa Cantone (0009-0001-5049-4614, Popular University of Cesar), Michela Atzeni (0000-0002-0645-3006, Popular University of Cesar), Enzo Tramontano (0000-0002-4849-0980, University of Cagliari), Stefano Lorrai (Popular University of Cesar), Fabrizio Bert (0000-0002-4329-9028, Department of Public Health), Antonio Egidio Nardi (0000-0002-2152-4669, Universidade Federal do Rio de Janeiro), Mauro Giovanni Carta (0000-0003-0706-9687, University of Cagliari), Giulia Cossu (0000-0002-1245-016X, Popular University of Cesar)
Year2026
Volume17
Pages1603347-1603347
Publication date2026-03-03
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2026.1603347
PMID41853084
OpenAlexW7133343734
LanguageEN
References cited47

Older adults generally displayed resilience during the pandemic. However, those with Hypothyroidism experienced increased depressive episodes and worsened quality of life, suggesting reduced stress adaptability despite hormone replacement therapy. This consideration highlights the potential need for interventions addressing both biological and psychosocial factors in managing depression risk in hypothyroid individuals

Cohort · Cohort study · Depression (economics · Euthyroid · Major depressive disorder · Psychological resilience · Psychosocial · Quality of life (healthcare · Thyroid Cancer Diagnosis and Treatment · Thyroid Disorders and Treatments · Vitamin D Research Studies

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