Mild Cognitive Impairment or Attention-Deficit/Hyperactivity Disorder in Older Adults? A Cross Sectional Study

Bibliographic Data

ID15525859
AuthorsFelippe Mendonça (0000-0003-0870-1832, D’Or Institute for Research and Education), Felipe Kenji Sudo (0000-0003-4738-1368, D’Or Institute for Research and Education, corresponding author), Gustavo Santiago‐Bravo (0000-0003-0001-363X, D’Or Institute for Research and Education), Gustavo Santiago-Bravo, Natália Oliveira (0000-0001-9852-7094, D’Or Institute for Research and Education), Naima Assunção (0000-0002-1262-8765, D’Or Institute for Research and Education), Fernanda Rodrigues (0000-0003-4830-1104, Universidade Federal do Rio de Janeiro), Rejane Soares (D’Or Institute for Research and Education), Victor Calil (0000-0002-1389-2445, D’Or Institute for Research and Education), Gabriel Bernardes (0000-0001-9472-7531, D’Or Institute for Research and Education), Pilar Erthal (0000-0002-6178-3251, D’Or Institute for Research and Education), Cláudia Drummond (0000-0002-6906-9335, Universidade Federal do Rio de Janeiro), Fernanda Tovar‐Moll (0000-0002-0292-5985, D’Or Institute for Research and Education), Fernanda Tovar-Moll, Paulo Mattos (0000-0003-0709-3783, Universidade Federal do Rio de Janeiro)
Year2021
Volume12
Pages737357-737357
Publication date2021-09-20
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2021.737357
PMID34616321
OpenAlexW3199288764
LanguageEN
Citations received2
References cited39

Background: Attention-Deficit/Hyperactivity Disorder (ADHD) is a highly prevalent neurodevelopmental condition, which may be associated with life-enduring cognitive dysfunction. It has been hypothesized that age-related cognitive decline may overlap with preexisting deficits in older ADHD patients, leading to increased problems to manage everyday-life activities. This phenomenon may mimic neurodegenerative disorders, in particular Mild Cognitive Impairment (MCI). This cross-sectional study aims to assess cognitive and behavioral differences between older subjects with ADHD and MCI. Methods: A total of 107 older participants (41 controls; 40 MCI and 26 ADHD; mean age = 67.60 ± 7.50 years; mean schooling = 15.14 ± 2.77 years; 65.4% females) underwent clinical, cognitive, and behavioral assessments by a multidisciplinary team at the Memory Clinic, D'Or Institute for Research and Education, Rio de Janeiro, Brazil. Mean scores in neuropsychological tasks and behavioral scales were compared across groups. Results: Participants with ADHD showed poorer performances than controls in episodic memory and executive function with large effect-sizes. Performances were comparable between MCI and ADHD for all domains. Discussion: MCI and ADHD in older individuals are dissociated clinical entities with overlapping cognitive profiles. Clinicians ought to be aware of these converging phenotypes to avoid misdiagnosis

Cognition · Cross-sectional study · Executive functions · Neuropsychology · Psychiatry · Working memory · Attention Deficit Hyperactivity Disorder · Clinical Psychology · Cognitive Functions and Memory · Medicine · Psychology

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