Narp-related alterations in the excitatory and inhibitory circuitry of socially isolated mice

Developmental insights and implications for autism spectrum disorder

Bibliographic Data

ID15525987
AuthorsYasunari Yamaguchi (0000-0002-9821-5100, Wakayama Medical University), Kazuya Okamura (0000-0002-4665-4849, Wakayama Medical University), Kazuhiko Yamamuro (0000-0002-4362-3262, Nara Medical University), Kazuki Okumura (0000-0002-3019-7049, Nara Medical University), Takashi Komori (0000-0003-3778-2993, Nara Medical University), Michihiro Toritsuka (0000-0001-6891-4173, Nara Medical University), Ryohei Takada (Nara Medical University), Yosuke Nishihata (Nara Medical University), Daisuke Ikawa (Nara Medical University), Takahira Yamauchi (0000-0001-9402-5062, Nara Medical University), Manabu Makinodan (0000-0003-4339-9413, Nara Medical University), Hiroki Yoshino (0000-0002-5955-8143, Nara Medical University), Yasuhiko Saito (0000-0002-0148-6597, Nara University), Hideo Matsuzaki (0000-0002-6869-1261, University of Fukui), Taishiro Kishimoto (0000-0003-0557-8648, Nara Medical University), Toshifumi Kishimoto, Sohei Kimoto (0000-0002-3148-690X, Wakayama Medical University, corresponding author)
Year2024
Volume15
Pages1403476-1403476
Publication date2024-06-06
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2024.1403476
PMID38903649
OpenAlexW4399523618
LanguageEN
References cited70

Our study highlights the role of electrophysiological properties, as well as NARP and PV expression in the PFC in mediating the developmental consequences of social isolation on behavior

Autism · Autism spectrum disorder · Biology · Cognition · Developmental psychology · Electrophysiology · Excitatory postsynaptic potential · Inhibitory postsynaptic potential · Juvenile · Parvalbumin · Prefrontal cortex · Social isolation · Autism Spectrum Disorder Research · Genetics and Neurodevelopmental Disorders · Neuroscience · Obsessive-Compulsive Spectrum Disorders · Psychology · Genetics

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