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Psychiatric safety associated with hormone replacement therapy for menopausal symptoms

A real-world study of the FDA adverse event reporting system

Bibliographic Data

ID15526397
AuthorsNan Chen (0000-0001-8454-079X, Shenzhen University Health Science Center, corresponding author), Lei Li (0000-0002-0388-7933, Shenzhen Second People's Hospital), Chunli Fu (0000-0003-4378-0863, Qilu Hospital of Shandong University), Chun-li Fu, Yi Ren (0000-0001-8876-5523, Shenzhen Second People's Hospital)
Year2025
Volume16
Pages1614087-1614087
Publication date2025-06-27
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2025.1614087
PMID40656051
OpenAlexW4411731273
LanguageEN
References cited31

It is necessary to conduct personalized risk stratification in HRT management, prioritizing age, administration route, and regimen type. While, further clinical investigations are needed to validate these findings and refine HRT safety strategies

Adverse effect · Adverse Event Reporting System · Confounding · Estrogen · Hormone replacement therapy (female-to-male · Menopause · Odds ratio · Progestogen · Testosterone (patch · Endometriosis Research and Treatment · Estrogen and related hormone effects · Medicine · Menopause: Health Impacts and Treatments · Internal Medicine

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Citation velocityhistorical
Highly citedNo

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