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Treatment of Early Onset Schizophrenia

Recent Trends, Challenges and Future Considerations

Bibliographic Data

ID15526794
AuthorsNora S Vyas (0000-0002-4784-5559, National Institute of Mental Health, corresponding author), Nitin Gogtay (National Institutes of Health)
Year2012
Volume3
Pages29-29
Publication date2012-01-01
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2012.00029
PMID22485097
PMCIDPMC3317175
OpenAlexW2131656600
LanguageEN
Citations received4

Early onset schizophrenia (onset before adulthood) is a rare, severe, and chronic form of schizophrenia. The clinical presentation of schizophrenia at this unusually early age of onset has been associated with premorbid developmental abnormalities, poor response to neuroleptic treatment, greater admission rates, and poor prognosis. This is a brief, condensed review of current treatment strategies for the early onset population highlighting the need for novel treatment strategies for these generally treatment-refractory cases. Based on the current literature, second-generation antipsychotics remain the mainstay of treatment, although current medications provide suboptimal response at best. Based on the adult literature, combining antipsychotic treatment with psychotherapeutic intervention may be a more comprehensive treatment strategy. Indeed, early detection, identification of relevant biomarkers, coupled with advancing knowledge of the neurochemical and neuroanatomic pathways may help design informed and novel treatment strategies

Perspective (graphical · Psychiatry · Schizophrenia (object-oriented programming · Attention Deficit Hyperactivity Disorder · Bipolar Disorder and Treatment · Medicine · Psychology · Schizophrenia research and treatment

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Citations per year0.33
Citation span2014 - 2022 (9)
Highly citedNo

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