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A Research of Methamphetamine Induced Psychosis in 1,430 Individuals With Methamphetamine Use Disorder

Clinical Features and Possible Risk Factors

Bibliographic Data

ID15526809
AuthorsHong Gan, Hong‐Seng Gan (0000-0003-3777-3640, Shanghai Jiao Tong University), Yan Zhao (0009-0007-8186-9443, Shanghai Mental Health Center), Haifeng Jiang (0000-0002-7993-461X), Hai-feng Jiang (0000-0001-8499-2825, Shanghai Jiao Tong University), Youwei Zhu (0000-0001-7891-3297, Shanghai Mental Health Center), Tianzhen Chen (0000-0001-6105-8749, Shanghai Jiao Tong University), Haoye Tan (0000-0002-9689-0583, Shanghai Jiao Tong University), Na Zhong (0000-0002-4656-2936, Shanghai Mental Health Center), Jiang Du (0000-0003-4014-1070, Shanghai Jiao Tong University), Min Zhao (0000-0002-2500-3035, Shanghai Mental Health Center, corresponding author)
Year2018
Volume9
Pages551-551
Publication date2018-11-06
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2018.00551
PMID30459651
OpenAlexW2899853590
LanguageEN
Citations received1
References cited46

Background and Aims: Methamphetamine (MA) abuse is commonly associated with the development of psychotic symptoms. The predictors and related risk factors of MA induced psychosis (MIP) are poorly understood. We investigated the occurrence of MIP, and analyzed the clinical features and possible risk factors among individuals with MA use disorder Method: One thousand four hundred and thirty participants with MA use disorder were recruited from compulsory rehabilitation centers in Shanghai. A structured questionnaire including demographic characteristics, drug use history, visual analog scales, Beck Depression Inventory-13 (BDI-13), and Hamilton anxiety scale-14 (HAMA-14) were used to collect clinical related information. Fifty-six participants had accomplished the test of CogState Battery. Results: Among the 1430 individuals with MA use disorder, 37.1% were diagnosed as MIP according DSM-IV. There were significant differences in age, marital status, age of drug use onset, MA use years, Average MA use dose, interval of MA use, maximum dose, concurrent use of alcohol, and other drugs, VAS score, MA dependence, BDI-13 scores, HAMA-14 scores, verbal learning memory, and visual learning memory between the MIP group and the none MIP group ( P p = 0.011), average drug use dose (OR = 1.800, p = 0.015), craving score (OR = 1.069, p = 0.031), MA dependence (OR = 2.214, p p Conclusion: Individuals with MIP had more severe drug use problems, emotional symptoms and cognitive impairment. Earlier onset of drug use, higher quantity of drug use, higher craving, middle or severe drug use disorder and more anxiety symptoms may be related risk factors of MIP

Bipolar disorder · Cognition · Methamphetamine · Psychiatry · Psychosis · Attention Deficit Hyperactivity Disorder · Clinical Psychology · Medicine · Neurotransmitter Receptor Influence on Behavior · Psychology · Schizophrenia research and treatment

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Citations per year0.5
Citation span2024 - 2024 (1)
Highly citedNo

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