Disrupted Causal Connectivity Anchored on the Right Anterior Insula in Drug-Naive First-Episode Patients With Depressive Disorder

Bibliographic Data

ID15527400
AuthorsHaiyan Xie (0000-0002-8322-1989, Zhejiang University), Qinger Guo (Zhejiang University), Jinfeng Duan (Zhejiang University), Xize Jia (0000-0003-4698-8723, Zhejiang Normal University), Weihua Zhou (0000-0002-6039-959X, Zhejiang University), Haozhe Sun (0000-0002-3625-2870, Heriot-Watt University), Ping Fang (0000-0002-6523-7151, Zhejiang University), Hong Yang (0000-0003-1416-0526, Zhejiang University, corresponding author)
Year2022
Volume13
Pages858768-858768
Publication date2022-05-18
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2022.858768
PMID35664465
OpenAlexW4280607546
LanguageEN
References cited41

Our results indicated disrupted causal connectivity among the default mode network (DMN), the central executive network (CEN), and SN in drug-naive first-episode MDD patients. Especially, our results suggest a unique role for rAI in the ordered or hierarchical information processing, presumed to include bottom-up and top-down reciprocal influences among the three networks in MDD

Audiology · Cognition · Default mode network · Drug · Drug-naïve · Functional magnetic resonance imaging · Insula · Major depressive disorder · Neuroimaging · Precuneus · Psychiatry · Resting state fMRI · Superior frontal gyrus · Advanced MRI Techniques and Applications · Functional Brain Connectivity Studies · Medicine · Mental Health Research Topics · Neuroscience · Psychology

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