Mendelian randomization reveals no associations of genetically-predicted obstructive sleep apnea with the risk of type 2 diabetes, nonalcoholic fatty liver disease, and coronary heart disease
Bibliographic Data
| ID | 15527426 |
|---|---|
| Authors | Xiaoxu Ding (0009-0008-1530-3481, China Medical University), Lanqing Zhao (0009-0004-0381-7945, China Medical University), Xiangguo Cui (China Medical University), Qi Li (0000-0003-3042-3584, China Medical University), Li Qi (0000-0002-7224-1327), Yu Chen (0000-0002-0557-4316, China Medical University, corresponding author) |
| Year | 2023 |
| Volume | 14 |
| Pages | 1068756-1068756 |
| Publication date | 2023-02-09 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Psychiatry (JOURNAL) |
| Journal identifiers | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Publisher | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2023.1068756 |
| PMID | 36846222 |
| OpenAlex | W4319759448 |
| Language | EN |
| References cited | 50 |
This MR study reveals that genetic liability to OSA might not be associated with the risk of T2D after the removal of obesity-related instruments. Besides, no causal association was observed between NAFLD and CHD. Further studies should be carried out to verify our findings
Biology · Cardiology · Coronary heart disease · Diabetes mellitus · Disease · Fatty liver · Gene · Genetic variants · Genotype · Mendelian randomization · Nonalcoholic fatty liver disease · Obstructive sleep apnea · Sleep apnea · Type 2 diabetes · Gastroesophageal reflux and treatments · Medicine · Obstructive Sleep Apnea Research · Voice and Speech Disorders · Endocrinology · Genetics · Internal Medicine
| Citation velocity | historical |
|---|---|
| Highly cited | No |